Literature DB >> 8019961

Trisomy 6 as the sole chromosome abnormality in myeloid disorders.

P Jonveaux1, P Fenaux, R Berger.   

Abstract

Trisomy 6 was the sole chromosomal abnormality detected in two patients with myeloid disorders in relapse. One had a refractory anemia with excess of blasts and the other acute myeloblastic leukemia. Simple trisomy 6 has been reported in patients with myeloid disorders, marrow hypoplasia, acute myeloid leukemia, and "preleukemia." The prognostic significance of this nonrandom chromosomal abnormality is discussed.

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Mesh：

Year:  1994        PMID： 8019961     DOI： 10.1016/0165-4608(94)90015-9

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  4 in total

1.  Trisomy 6 as the sole stemline abnormality in a patient with acute monocytic leukemia: a case report.

Authors:  Masahiro Manabe; Reiko Asada; Yuji Hagiwara; Dai Momose; Yasuyoshi Sugano; Takeshi Mazaki; Ki-Ryang Koh
Journal:  Am J Blood Res       Date:  2018-04-05

2.  Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene.

Authors:  Luoping Zhang; Qing Lan; Weihong Guo; Alan E Hubbard; Guilan Li; Stephen M Rappaport; Cliona M McHale; Min Shen; Zhiying Ji; Roel Vermeulen; Songnian Yin; Nathaniel Rothman; Martyn T Smith
Journal:  Carcinogenesis       Date:  2011-01-07       Impact factor: 4.944

3.  Trisomy chromosome 6 as a sole cytogenetic abnormality in acute myeloid leukemia.

Authors:  Monika Gupta; Nita Radhakrishnan; Manoranjan Mahapatra; Renu Saxena
Journal:  Turk J Haematol       Date:  2015-03-05       Impact factor: 1.831

4.  Analysis of acute myeloid leukemia in Korean patients with sole trisomy 6.

Authors:  Shinae Yu; Min-Jung Kwon; Seung-Tae Lee; Hee-Yeon Woo; Hyosoon Park; Sun-Hee Kim
Journal:  Ann Lab Med       Date:  2014-08-21       Impact factor: 3.464
  4 in total

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