Literature DB >> 8019712

Antibodies to beta-adrenergic receptors disclosing agonist-like properties in idiopathic dilated cardiomyopathy and Chagas' heart disease.

M B Rosenbaum1, P A Chiale, D Schejtman, M Levin, M V Elizari.   

Abstract

Recent studies confirm the existence of antibodies (Abs) to beta-adrenoceptors in patients with idiopathic dilated cardiomyopathy and Chagas' heart disease. These Abs can be shown to exert both stimulatory and inhibitory effects, which may play a role in the development of the cardiac abnormalities known to occur in these diseases, including advanced heart failure. The hypothesis is advanced that Chagas' heart disease and some forms of idiopathic dilated cardiomyopathy may represent, at least partially, a form of "adrenergic cardiomyopathy."

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Year:  1994        PMID: 8019712     DOI: 10.1111/j.1540-8167.1994.tb01174.x

Source DB:  PubMed          Journal:  J Cardiovasc Electrophysiol        ISSN: 1045-3873


  19 in total

1.  Mauricio Rosenbaum: the internationally renowned electrocardiologist south of the equator (1921-2003).

Authors:  Marcelo V Elizari
Journal:  Ann Noninvasive Electrocardiol       Date:  2008-01       Impact factor: 1.468

Review 2.  Role of autoantibodies in the physiopathology of Chagas' disease.

Authors:  Emiliano Horacio Medei; José Hamilton Matheus Nascimento; Roberto Coury Pedrosa; Antônio Carlos Campos de Carvalho
Journal:  Arq Bras Cardiol       Date:  2008-10       Impact factor: 2.000

3.  Autoimmune hypertensive syndrome.

Authors:  David C Kem; Xichun Yu; Eugene Patterson; Shijun Huang; Stavros Stavrakis; Bela Szabo; Leann Olansky; Jon McCauley; Madeleine W Cunningham
Journal:  Hypertension       Date:  2007-10-08       Impact factor: 10.190

4.  Development of cardiomyopathy and atrial tachyarrhythmias associated with activating autoantibodies to beta-adrenergic and muscarinic receptors.

Authors:  Xichun Yu; Eugene Patterson; Stavros Stavrakis; Shijun Huang; Isabel De Aos; Sean Hamlett; Madeleine W Cunningham; Ralph Lazarra; David C Kem
Journal:  J Am Soc Hypertens       Date:  2009-01-20

5.  Antibodies from Trypanosoma cruzi infected mice recognize the second extracellular loop of the beta 1-adrenergic and M2-muscarinic receptors and regulate calcium channels in isolated cardiomyocytes.

Authors:  A Mijares; L Verdot; N Peineau; B Vray; J Hoebeke; J Argibay
Journal:  Mol Cell Biochem       Date:  1996 Oct-Nov       Impact factor: 3.396

6.  Structural and functional complexity of the humoral response against the Trypanosoma cruzi ribosomal P2 beta protein in patients with chronic Chagas' heart disease.

Authors:  E Mahler; J Hoebeke; M J Levin
Journal:  Clin Exp Immunol       Date:  2004-06       Impact factor: 4.330

7.  Atrial tachycardia provoked in the presence of activating autoantibodies to β2-adrenergic receptor in the rabbit.

Authors:  Hongliang Li; Benjamin J Scherlag; David C Kem; Caitlin Zillner; Shailesh Male; Sorkko Thirunavukkarasu; Xiaohua Shen; Jan V Pitha; Madeleine W Cunningham; Ralph Lazzara; Xichun Yu
Journal:  Heart Rhythm       Date:  2012-11-23       Impact factor: 6.343

8.  Mechanism of anti-beta-adrenoceptor antibody mediated myocardial damage in dilated cardiomyopathy.

Authors:  Y Liao; L Cheng; Y Tu; J Zhang; J Dong; S Li; Y Tian; Y Peng
Journal:  J Tongji Med Univ       Date:  1997

9.  Anti-beta1-adrenergic receptor autoantibodies in patients with chronic Chagas heart disease.

Authors:  V Labovsky; C R Smulski; K Gómez; G Levy; M J Levin
Journal:  Clin Exp Immunol       Date:  2007-04-05       Impact factor: 4.330

Review 10.  Drug-like actions of autoantibodies against receptors of the autonomous nervous system and their impact on human heart function.

Authors:  L R Herda; S B Felix; F Boege
Journal:  Br J Pharmacol       Date:  2012-06       Impact factor: 8.739

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