Literature DB >> 8019192

New treatments for dementia. Myth, magic, and science.

R Ganesan1, T Standish, D W Molloy, P Darzins, J B Orange.   

Abstract

Dementia could affect 778,000 Canadians by the year 2031. While current treatment is mainly supportive, a race to find new treatments for this dreaded disease takes varied approaches and currently accounts for 10% of drug company resources. Tacrine is the first drug licensed by the US Food and Drug Administration for use in Alzheimer's disease. New treatments raise several ethical issues and involve society's attitude toward death and dying.

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Year:  1994        PMID: 8019192      PMCID: PMC2380209     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  29 in total

1.  Treatment for Alzheimer's disease?

Authors:  J H Growdon
Journal:  N Engl J Med       Date:  1992-10-29       Impact factor: 91.245

2.  Treatment for life-threatening illness.

Authors:  P Darziņs; D W Molloy; C Harrison
Journal:  N Engl J Med       Date:  1993-09-02       Impact factor: 91.245

3.  Comparative study of caffeine with other stimulants in university students.

Authors:  M Vojtĕchovský; V Safratová
Journal:  Act Nerv Super (Praha)       Date:  1972

4.  "Smart-drug, smart-food" fad winning converts despite scientists' scepticism.

Authors:  B Evenson
Journal:  CMAJ       Date:  1993-02-15       Impact factor: 8.262

5.  Death gives birth to the nervous system. But how?

Authors:  M Barinaga
Journal:  Science       Date:  1993-02-05       Impact factor: 47.728

6.  Effect of a new nootropic agent, CGS 5649B, on cognition, function, and behavior in dementia.

Authors:  D W Molloy; G H Guyatt; T Standish; A Willan; W McIlroy; J D'Souza; G Brown; C Mondadori
Journal:  J Gen Intern Med       Date:  1993-08       Impact factor: 5.128

Review 7.  The efficacy of the cerebral metabolic enhancers in the treatment of senile dementia.

Authors:  R J Branconnier
Journal:  Psychopharmacol Bull       Date:  1983

8.  Nootropics: status and prospects.

Authors:  T M Itil
Journal:  Biol Psychiatry       Date:  1983-05       Impact factor: 13.382

Review 9.  L-deprenyl in the treatment of mild dementia of the Alzheimer type: results of a 15-month trial.

Authors:  W J Burke; W H Roccaforte; S P Wengel; B L Bayer; A E Ranno; N K Willcockson
Journal:  J Am Geriatr Soc       Date:  1993-11       Impact factor: 5.562

10.  A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease. The Tacrine Collaborative Study Group.

Authors:  K L Davis; L J Thal; E R Gamzu; C S Davis; R F Woolson; S I Gracon; D A Drachman; L S Schneider; P J Whitehouse; T M Hoover
Journal:  N Engl J Med       Date:  1992-10-29       Impact factor: 91.245

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