Literature DB >> 8017394

Treatment of achalasia: the best of both worlds.

S Abid1, G Champion, J E Richter, R McElvein, R L Slaughter, R E Koehler.   

Abstract

OBJECTIVE: To conduct a retrospective analysis of one center's experience with treating achalasia over 4 yr with skilled gastroenterologists using primarily the Rigiflex balloon dilator and with a senior surgeon performing Heller myotomies.
METHODS: Newly diagnosed cases of achalasia were identified by a computer search of hospital records. Charts were reviewed for the presence/severity of dysphagia, regurgitation, heartburn, and chest pain. Weight loss was also recorded. Esophageal manometries and barium swallows were reviewed. Choice of treatment was made freely by patients. With an a priori definition of success, follow-up was conducted by telephone interviews.
RESULTS: A total of 45 achalasia patients (mean age, 46 yr; 32 females, 13 males) were identified with a symptoms-frequency as follows: dysphagia, 100%; regurgitation, 78%; heartburn, 50%; and chest pain, 42%. Mean weight loss was 17.5 pounds. Primary treatment was pneumatic dilation in 36 patients and surgery in nine patients. In a total of 45 pneumatic dilations, three (6.6%) were complicated by perforation. Five (14%) patients required repeat dilation. Mean duration of follow-up for pneumatic dilation and surgery was 27 months and 20.8 months, respectively. The overall excellent-good success rates were: pneumatic dilation 88% and surgery 89%. In comparing the efficacy of pneumatic dilation versus surgery, all symptoms were improved significantly (p < 0.01) in both groups, except heartburn, which increased postmyotomy.
CONCLUSIONS: If both procedures are available by skilled operators, pneumatic dilation and surgery are equally effective in the treatment of achalasia.

Entities:  

Mesh:

Year:  1994        PMID: 8017394

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN: 0002-9270            Impact factor:   10.864


  19 in total

1.  Effects of previous treatment on results of laparoscopic Heller myotomy for achalasia.

Authors:  M G Patti; C V Feo; M Arcerito; M De Pinto; A Tamburini; U Diener; W Gantert; L W Way
Journal:  Dig Dis Sci       Date:  1999-11       Impact factor: 3.199

Review 2.  Data analyses and perspectives on laparoscopic surgery for esophageal achalasia.

Authors:  Kazuto Tsuboi; Nobuo Omura; Fumiaki Yano; Masato Hoshino; Se-Ryung Yamamoto; Shunsuke Akimoto; Takahiro Masuda; Hideyuki Kashiwagi; Katsuhiko Yanaga
Journal:  World J Gastroenterol       Date:  2015-10-14       Impact factor: 5.742

3.  Botulinum toxin versus pneumatic dilatation in the treatment of achalasia: a randomised trial.

Authors:  M F Vaezi; J E Richter; C M Wilcox; P L Schroeder; S Birgisson; R L Slaughter; R E Koehler; M E Baker
Journal:  Gut       Date:  1999-02       Impact factor: 23.059

4.  Untoward effects of esophageal botulinum toxin injection in the treatment of achalasia.

Authors:  E Y Eaker; J M Gordon; S B Vogel
Journal:  Dig Dis Sci       Date:  1997-04       Impact factor: 3.199

5.  Surgical treatment analysis of idiopathic esophageal achalasia.

Authors:  José Luis Braga de Aquino; Marcelo Manzano Said; Douglas Rizzanti Pereira; Paula Casals do Amaral; Juliana Carolina Alves Lima; Vânia Aparecida Leandro-Merhi
Journal:  Arq Bras Cir Dig       Date:  2015 Apr-Jun

Review 6.  Updated Systematic Review of Achalasia, with a Focus on POEM Therapy.

Authors:  Mitchell S Cappell; Stavros Nicholas Stavropoulos; David Friedel
Journal:  Dig Dis Sci       Date:  2019-08-27       Impact factor: 3.199

7.  Efficacy and safety of cardiomyotomy in patients with achalasia after failure of pneumatic dilatation.

Authors:  J Ponce; M Juan; V Garrigues; S Pascual; J Berenguer
Journal:  Dig Dis Sci       Date:  1999-11       Impact factor: 3.199

8.  Long-term results of graded pneumatic dilatation under endoscopic guidance in patients with primary esophageal achalasia.

Authors:  Ahmet Dobrucali; Yusuf Erzin; Murat Tuncer; Ahmet Dirican
Journal:  World J Gastroenterol       Date:  2004-11-15       Impact factor: 5.742

9.  The cost-effectiveness of treatment strategies for achalasia.

Authors:  J Barry O'Connor; Mendel E Singer; Thomas F Imperiale; Michael F Vaezi; Joel E Richter
Journal:  Dig Dis Sci       Date:  2002-07       Impact factor: 3.199

Review 10.  Are idiopathic and Chagasic achalasia two different diseases?

Authors:  Fernando A M Herbella; Daniel R C F Oliveira; Jose C Del Grande
Journal:  Dig Dis Sci       Date:  2004-03       Impact factor: 3.199

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