Literature DB >> 8017061

[The evaluation in hamadryas baboons of the possibility for the specific prevention of Ebola fever].

V V Mikhaĭlov, I V Borisevich, N K Chernikova, N V Potryvaeva, V P Krasnianskiĭ.   

Abstract

The protective role of virus-neutralizing antibody was demonstrated in Ebola virus-infected animals (Papio hamadryas) used in experiments on the development of passive humoral immunity by using specific immunoglobulin. Two immunizations of the monkeys with purified concentrated Ebola virus antigen with complete Freund adjuvant was shown to confirm intensive immunity to subsequent challenge protecting 80% of the immunized animals. It is concluded that effective preparations may be developed for specific prophylaxis of Ebola fever.

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Year:  1994        PMID: 8017061

Source DB:  PubMed          Journal:  Vopr Virusol        ISSN: 0507-4088


  23 in total

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Review 4.  Prospects for immunisation against Marburg and Ebola viruses.

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Authors:  Thomas W Geisbert; Lisa E Hensley; Tom Larsen; Howard A Young; Douglas S Reed; Joan B Geisbert; Dana P Scott; Elliott Kagan; Peter B Jahrling; Kelly J Davis
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9.  Disease modeling for Ebola and Marburg viruses.

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Journal:  Dis Model Mech       Date:  2009 Jan-Feb       Impact factor: 5.758

Review 10.  Neglected filoviruses.

Authors:  Robin Burk; Laura Bollinger; Joshua C Johnson; Jiro Wada; Sheli R Radoshitzky; Gustavo Palacios; Sina Bavari; Peter B Jahrling; Jens H Kuhn
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