Literature DB >> 8016420

Diagnosis of antiphospholipid antibodies.

M Petri1.   

Abstract

The antiphospholipid antibody syndrome consists of a presentation with venous thrombosis, arterial thrombosis (or vasculopathy), recurrent pregnancy loss, or thrombocytopenia, in the setting of high-titer anticardiolipin antibody or lupus anticoagulant. Characteristics of the lupus anticoagulant (an antibody detected by a functional assay) and anticardiolipin antibody are reviewed, in light of new information on the role of plasma proteins, especially B2-glycoprotein I. The advantages and disadvantages of screening and confirmatory assays for lupus anticoagulant are detailed, as well as modifications of the anticardiolipin antibody assay to improve sensitivity and specificity.

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Year:  1994        PMID: 8016420

Source DB:  PubMed          Journal:  Rheum Dis Clin North Am        ISSN: 0889-857X            Impact factor:   2.670


  7 in total

1.  Histological appearance of the intra-osseous vessels of the femoral head in aseptic osteonecrosis of the hip, with or without antiphospholipid antibodies.

Authors:  M Laroche; I Ludot; M Thiechart; G Viguier; C Dromer; B Mazières
Journal:  Clin Rheumatol       Date:  1997-06       Impact factor: 2.980

2.  Clinical features associated with a positive anticardiolipin antibody in Irish patients with systemic lupus erythematosus.

Authors:  I S Gourley; S A McMillan; A L Bell
Journal:  Clin Rheumatol       Date:  1996-09       Impact factor: 2.980

Review 3.  [Diagnosis of the antiphospholipid syndrome in anticoagulated patients].

Authors:  M Mohren; T Daikeler; A Engel; I Guenaydin; I Koetter
Journal:  Z Rheumatol       Date:  2004-12       Impact factor: 1.372

4.  Simultaneous deep vein thrombosis and transverse myelitis with negative serology as a first sign of antiphospholipid syndrome: a case report and review of the literature.

Authors:  Dan Carter; David Olchovsky; Hagit Yonath; Pnina Langevitz; David Ezra
Journal:  Clin Rheumatol       Date:  2005-10-19       Impact factor: 2.980

5.  Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus.

Authors:  L Casciola-Rosen; A Rosen; M Petri; M Schlissel
Journal:  Proc Natl Acad Sci U S A       Date:  1996-02-20       Impact factor: 11.205

Review 6.  The antiphospholipid syndrome: what are we really measuring? How do we measure it? And how do we treat it?

Authors:  Thomas L Ortel
Journal:  J Thromb Thrombolysis       Date:  2006-02       Impact factor: 2.300

7.  Transverse myelitis: a complication of systemic lupus erythematosus that is associated with the antiphospholipid syndrome.

Authors:  A E Smyth; I N Bruce; S A McMillan; A L Bell
Journal:  Ulster Med J       Date:  1996-05
  7 in total

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