| Literature DB >> 8016163 |
Abstract
Erythropoietin (Epo) induces a dose-dependent increase in intracellular free calcium concentration ([Cai]) in single human BFU-E derived erythroblasts, which is specific for stage of differentiation and mediated through a voltage-independent ion channel permeable to calcium. This minireview examines the regulation of calcium channels by Epo during normal erythroid differentiation, as a model to delineate the immediate signaling events which follow interaction of Epo with its receptor.Entities:
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Year: 1994 PMID: 8016163 DOI: 10.3181/00379727-206-43756
Source DB: PubMed Journal: Proc Soc Exp Biol Med ISSN: 0037-9727