Literature DB >> 8016146

Primary structure and characterization of a small-conductance inwardly rectifying potassium channel from human hippocampus.

F Périer1, C M Radeke, C A Vandenberg.   

Abstract

We have isolated a human hippocampus cDNA that encodes an inwardly rectifying potassium channel, termed HIR (hippocampal inward rectifier), with strong rectification characteristics. Single-channel recordings indicate that the HIR channel has an unusually small conductance (13 pS), distinguishing HIR from other cloned inward rectifiers. RNA blot analyses show that HIR transcripts are present in heart, skeletal muscle, and several different brain regions, including the hippocampus.

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Year:  1994        PMID： 8016146      PMCID： PMC44174          DOI： 10.1073/pnas.91.13.6240

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  29 in total

1.  Ohmic conductance through the inwardly rectifying K channel and blocking by internal Mg2+.

Authors:  H Matsuda; A Saigusa; H Irisawa
Journal:  Nature       Date:  1987 Jan 8-14       Impact factor: 49.962

2.  A potential- and time-dependent blockade of inward rectification in frog skeletal muscle fibres by barium and strontium ions.

Authors:  N B Standen; P R Stanfield
Journal:  J Physiol       Date:  1978-07       Impact factor: 5.182

3.  Inwardly rectifying potassium current in rat fetal and neonatal ventricular cardiomyocytes.

Authors:  H Masuda; N Sperelakis
Journal:  Am J Physiol       Date:  1993-10

4.  Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.

Authors:  O P Hamill; A Marty; E Neher; B Sakmann; F J Sigworth
Journal:  Pflugers Arch       Date:  1981-08       Impact factor: 3.657

5.  Single K+ channel currents of anomalous rectification in cultured rat myotubes.

Authors:  H Ohmori; S Yoshida; S Hagiwara
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

6.  Conductance properties of single inwardly rectifying potassium channels in ventricular cells from guinea-pig heart.

Authors:  B Sakmann; G Trube
Journal:  J Physiol       Date:  1984-02       Impact factor: 5.182

7.  Single channel analysis of the inward rectifier K current in the rabbit ventricular cells.

Authors:  M Kameyama; T Kiyosue; M Soejima
Journal:  Jpn J Physiol       Date:  1983

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Authors:  B Hille; W Schwarz
Journal:  J Gen Physiol       Date:  1978-10       Impact factor: 4.086

9.  Barium-induced blockade of the inward rectifier in calf Purkinje fibres.

Authors:  D DiFrancesco; A Ferroni; S Visentin
Journal:  Pflugers Arch       Date:  1984-12       Impact factor: 3.657

10.  Ionic blockage of sodium channels in nerve.

Authors:  A M Woodhull
Journal:  J Gen Physiol       Date:  1973-06       Impact factor: 4.086
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  37 in total

1.  Effects of intra- and extracellular acidifications on single channel Kir2.3 currents.

Authors:  G Zhu; S Chanchevalap; N Cui; C Jiang
Journal:  J Physiol       Date:  1999-05-01       Impact factor: 5.182

2.  Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen's syndrome.

Authors:  Regina Preisig-Müller; Günter Schlichthörl; Tobias Goerge; Steffen Heinen; Andrea Brüggemann; Sindhu Rajan; Christian Derst; Rüdiger W Veh; Jürgen Daut
Journal:  Proc Natl Acad Sci U S A       Date:  2002-05-28       Impact factor: 11.205

3.  Assignment of the murine inwardly rectifying potassium channel IRK3 gene (Kcnj4) to the mouse chromosome 15.

Authors:  K Morishige; T Takumi; N Takahashi; H Koyama; H Kurachi; A Miyake; Y Murata; N G Copeland; D J Gilbert; N A Jenkins; Y Kurachi
Journal:  Mamm Genome       Date:  1997-09       Impact factor: 2.957

4.  The transoocyte voltage clamp: a non-invasive technique for electrophysiological experiments with Xenopus laevis oocytes.

Authors:  Dana Cucu; Jeannine Simaels; Danny Jans; Willy Van Driessche
Journal:  Pflugers Arch       Date:  2004-01-10       Impact factor: 3.657

5.  Secondary structure, membrane localization, and coassembly within phospholipid membranes of synthetic segments derived from the N- and C-termini regions of the ROMK1 K+ channel.

Authors:  I Ben-Efraim; Y Shai
Journal:  Protein Sci       Date:  1996-11       Impact factor: 6.725

6.  Interaction of Ba2+ with the pores of the cloned inward rectifier K+ channels Kir2.1 expressed in Xenopus oocytes.

Authors:  R C Shieh; J C Chang; J Arreola
Journal:  Biophys J       Date:  1998-11       Impact factor: 4.033

7.  IRK(1-3) and GIRK(1-4) inwardly rectifying K+ channel mRNAs are differentially expressed in the adult rat brain.

Authors:  C Karschin; E Dissmann; W Stühmer; A Karschin
Journal:  J Neurosci       Date:  1996-06-01       Impact factor: 6.167

8.  Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator.

Authors:  C M McNicholas; W B Guggino; E M Schwiebert; S C Hebert; G Giebisch; M E Egan
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-23       Impact factor: 11.205

9.  Modulation of inwardly rectifying currents in rat sympathetic neurones by muscarinic receptors.

Authors:  H S Wang; D McKinnon
Journal:  J Physiol       Date:  1996-04-15       Impact factor: 5.182

10.  [K+] dependence of open-channel conductance in cloned inward rectifier potassium channels (IRK1, Kir2.1).

Authors:  A N Lopatin; C G Nichols
Journal:  Biophys J       Date:  1996-08       Impact factor: 4.033
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