Literature DB >> 8015965

A novel peptide in the AKH/RPCH family isolated from the corpora cardiaca of the Emperor dragonfly, Anax imperator.

G Gäde1, M P Janssens, R Kellner.   

Abstract

Using a heterologous (in locusts and cockroaches) and a homologous bioassay, we have isolated the neuropeptide pGlu-Val-Asn-Phe-Ser-Pro-Ser-Trp-NH2 from extracts of corpora cardiaca of the Emperor dragonfly, Anax imperator. The sequence elucidation was achieved by Edman degradation of the deblocked peptide and by electrospray mass spectrometry. Low concentrations of the synthetic peptide injected into the Emperor dragonfly increased the hemolymph lipid concentration, suggesting a possible role of the peptide in lipid homeostasis during flight. Therefore, it is named Ani-AKH, Anax imperator adipokinetic hormone.

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Year:  1994        PMID： 8015965     DOI： 10.1016/0196-9781(94)90162-7

Source DB:  PubMed          Journal:  Peptides        ISSN： 0196-9781            Impact factor:   3.750


  5 in total

1.  Identification and functional characterization of two orphan G-protein-coupled receptors for adipokinetic hormones from silkworm Bombyx mori.

Authors:  Ying Shi; Haishan Huang; Xiaoyan Deng; Xiaobai He; Jingwen Yang; Huipeng Yang; Liangen Shi; Lijuan Mei; Jimin Gao; Naiming Zhou
Journal:  J Biol Chem       Date:  2011-10-18       Impact factor: 5.157

2.  Bombyx adipokinetic hormone receptor activates extracellular signal-regulated kinase 1 and 2 via G protein-dependent PKA and PKC but β-arrestin-independent pathways.

Authors:  Haishan Huang; Xiaobai He; Xiaoyan Deng; Guo Li; Guoyuan Ying; Yi Sun; Liangen Shi; Jeffrey L Benovic; Naiming Zhou
Journal:  Biochemistry       Date:  2010-12-02       Impact factor: 3.162

3.  A novel adipokinetic octapeptide found in the damselflies Pseudagrion inconspicuum and Ischnura senegalensis.

Authors:  M P Janssens; R Kellner; G Gde
Journal:  Biochem J       Date:  1994-09-01       Impact factor: 3.857

4.  SB 209670, a rationally designed potent nonpeptide endothelin receptor antagonist.

Authors:  E H Ohlstein; P Nambi; S A Douglas; R M Edwards; M Gellai; A Lago; J D Leber; R D Cousins; A Gao; J S Frazee
Journal:  Proc Natl Acad Sci U S A       Date:  1994-08-16       Impact factor: 11.205

5.  Molecular and functional characterization of adipokinetic hormone receptor and its peptide ligands in Bombyx mori.

Authors:  Chenggang Zhu; Haishan Huang; Rongsheng Hua; Guo Li; Dong Yang; Jiansong Luo; Cunxin Zhang; Liangen Shi; Jeffrey L Benovic; Naiming Zhou
Journal:  FEBS Lett       Date:  2009-04-02       Impact factor: 4.124
  5 in total

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