[Value of formalin-fixed, allogeneic veins for vessel substitution in long-term tests. Experimental studies of the problem of immunological reactions on RtH-1-incompatible various rat-donor-recipient combinations].

Experiments on an immunogenetically standardized inbred rat strain combination were necessary to determine whether immunological reactions have an effect on the increase and transformation processes of allogeneic formalin-fixed venous implants. By using a RtH-1-incompatible allogeneic strain combination we found that immunological mechanisms-humoral or cellbound-are insignificant to such venous implants. The formalin-fixing procedure caused the antigenicity to lose its effectiveness. Thus, the submitted material shows that immunological reactions are not responsible for delayed alterations in such venous implants.