Literature DB >> 8015572

The economic impact of multiple-gestation pregnancies and the contribution of assisted-reproduction techniques to their incidence.

T L Callahan1, J E Hall, S L Ettner, C L Christiansen, M F Greene, W F Crowley.   

Abstract

BACKGROUND: Although the medical complications associated with multiple-gestation pregnancies have been well documented, little is known about the effects of such pregnancies on the use of health care resources and the associated costs. This is an important issue because of the increasing use of assisted-reproduction techniques, which commonly result in multiple-gestation pregnancies.
METHODS: We determined hospital charges and the use of assisted-reproduction techniques (such as induction of ovulation, in vitro fertilization, and gamete intrafallopian transfer) for 13,206 pregnant women (11,986 with singleton pregnancies, 1135 with twin pregnancies, and 85 with more than two fetuses) who were admitted for delivery to Brigham and Women's Hospital, Boston, in 1986 through 1991 and their 14,033 neonates (11,671 singletons, 2144 twins, and 218 resulting from higher-order multiple gestations).
RESULTS: After we controlled for variables known to affect hospital charges, the predicted total charges to the family in 1991 for a singleton delivery were $9,845, as compared with $37,947 for twins ($18,974 per baby) and $109,765 for triplets ($36,588 per baby). Assisted-reproduction techniques were used in 2 percent of singleton, 35 percent of twin, and 77 percent of higher-order multiple-gestation pregnancies; such procedures were approximately equally divided between induction of ovulation alone and in vitro fertilization or gamete intrafallopian transfer.
CONCLUSIONS: Multiple-gestation pregnancies, a high proportion of which result from the use of assisted-reproduction techniques, dramatically increase hospital charges. If all the multiple gestations resulting from assisted-reproduction techniques, dramatically increase hospital charges. If all the multiple gestations resulting from assisted-reproduction techniques had been singleton pregnancies, the predicted savings to the health care delivery system in the study hospital alone would have been over $3 million per year. Although assisted reproduction provides tremendous benefits to families with infertility, the increased medical risks entailed by multiple-gestation pregnancies and the associated costs cannot be ignored. We suggest that more attention be paid to approaches to infertility that reduce the likelihood of multiple gestation.

Entities:  

Mesh:

Year:  1994        PMID: 8015572     DOI: 10.1056/NEJM199407283310407

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


  33 in total

Review 1.  Infertility: from a personal to a public health problem.

Authors:  A T Fidler; J Bernstein
Journal:  Public Health Rep       Date:  1999 Nov-Dec       Impact factor: 2.792

Review 2.  Bioethics for clinicians: 26. Assisted reproductive technologies.

Authors:  L Shanner; J Nisker
Journal:  CMAJ       Date:  2001-05-29       Impact factor: 8.262

3.  Incidence and perinatal outcome of multiple pregnancies after intracytoplasmic sperm injection compared to standard in vitro fertilization.

Authors:  D Bider; A Livshitz; I Tur Kaspa; A Shulman; J Levron; J Dor
Journal:  J Assist Reprod Genet       Date:  1999-05       Impact factor: 3.412

4.  The impact of the increasing number of multiple births on the rates of preterm birth and low birthweight: an international study.

Authors:  Béatrice Blondel; Michael D Kogan; Greg R Alexander; Nirupa Dattani; Michael S Kramer; Alison Macfarlane; Shi Wu Wen
Journal:  Am J Public Health       Date:  2002-08       Impact factor: 9.308

5.  The medical marketplace and the diffusion of technologies.

Authors:  R H Blank
Journal:  Health Care Anal       Date:  1996-11

6.  Economic implications of multiple births: inpatient hospital costs in the first 5 years of life.

Authors:  J Henderson; C Hockley; S Petrou; M Goldacre; L Davidson
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2004-11       Impact factor: 5.747

7.  The cost of prematurity: a case-control study of twins vs singletons.

Authors:  B Luke; H R Bigger; S Leurgans; D Sietsema
Journal:  Am J Public Health       Date:  1996-06       Impact factor: 9.308

8.  A prospective, randomized, multicenter trial of amnioreduction vs selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndrome.

Authors:  Timothy M Crombleholme; David Shera; Hanmin Lee; Mark Johnson; Mary D'Alton; Flint Porter; Jacquelyn Chyu; Richard Silver; Alfred Abuhamad; George Saade; Laurence Shields; David Kauffman; Joanne Stone; Craig T Albanese; Ray Bahado-Singh; Robert H Ball; Larissa Bilaniuk; Beverly Coleman; Diana Farmer; Vickie Feldstein; Michael R Harrison; Holly Hedrick; Jeffrey Livingston; Robert P Lorenz; David A Miller; Mary E Norton; William J Polzin; Julian N Robinson; Jack Rychik; Per L Sandberg; Istvan Seri; Erin Simon; Lynn L Simpson; Larisa Yedigarova; R Douglas Wilson; Bruce Young
Journal:  Am J Obstet Gynecol       Date:  2007-10       Impact factor: 8.661

9.  The transfer of two embryos instead of three to reduce the risk of multiple pregnancy: a retrospective analysis.

Authors:  P L Matson; J Browne; R Deakin; B Bellinge
Journal:  J Assist Reprod Genet       Date:  1999-01       Impact factor: 3.412

10.  Establishment of a low birth weight registry and initial outcomes.

Authors:  Elizabeth Eisenhauer; David E Uddin; Pam Albers; Sara Paton; Robert L Stoughton
Journal:  Matern Child Health J       Date:  2011-10
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.