Literature DB >> 8014511

Og4C3 circulating antigen: a marker of infection and adult worm burden in Wuchereria bancrofti filariasis.

S Chanteau1, J P Moulia-Pelat, P Glaziou, N L Nguyen, P Luquiaud, C Plichart, P M Martin, J L Cartel.   

Abstract

Og4C3 circulating filarial antigen was detected in the sera of 94.5% (259/274) of microfilaremic patients, 32% (239/751) of persons with presumption of filariasis, and 23% (11/48) of chronic filariasis patients. The antigen level was correlated with the microfilariae (Mf) density and patient age (P < .01). It remained stable in patients treated with microfilaricidal drugs. Og4C3 antigen, undetectable in Mf culture media, was demonstrated to be a rare somatic Mf antigen. It appears to be an excreted or secreted antigen from adult filaria. It could be used as a marker of infection and an indicator of adult worm burden.

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Year:  1994        PMID： 8014511     DOI： 10.1093/infdis/170.1.247

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  28 in total

1.  Immune responses to recombinant Brugia malayi pepsin inhibitor homolog (Bm-33) in patients with human lymphatic filariaisis.

Authors:  N S A Krushna; C Shiny; G Manokaran; S Elango; S Babu; R B Narayanan
Journal:  Parasitol Res       Date:  2010-10-07       Impact factor: 2.289

2.  Low density microfilaraemia as a causative agent in a case of unexplained ascitis of suspicious nature.

Authors:  Rahul Mannan; Tejinder Singh Bhasin; Mridu Manjari; Vatsala Misra
Journal:  J Clin Diagn Res       Date:  2013-07-01

3.  Semi-quantitative scoring of an immunochromatographic test for circulating filarial antigen.

Authors:  Cédric B Chesnais; François Missamou; Sébastien D S Pion; Jean Bopda; Frédéric Louya; Andrew C Majewski; Gary J Weil; Michel Boussinesq
Journal:  Am J Trop Med Hyg       Date:  2013-09-09       Impact factor: 2.345

4.  Cost-effective antigen testing for delimitation, monitoring and evaluation in bancroftian filariasis.

Authors:  L K Das; S P Pani; P Vanamail; G Vijayalakshmi; L J Debritto
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2012-01-31       Impact factor: 3.267

5.  Recombinant Wolbachia heat shock protein 60 (HSP60) mediated immune responses in patients with lymphatic filariasis.

Authors:  Chandanapurath Shiny; Nagampalli S A Krushna; Subash Babu; S Elango; Guruswamy Manokaran; Rangarajan Badri Narayanan
Journal:  Microbes Infect       Date:  2011-07-23       Impact factor: 2.700

6.  Epidemiological screening of lymphatic filariasis among immigrants using dipstick colloidal dye immunoassay.

Authors:  A Wan Omar; O Sulaiman; S Yusof; G Ismail; M S Fatmah; N Rahmah; A A Khairul
Journal:  Malays J Med Sci       Date:  2001-07

7.  Serum immune complexes as diagnostic and therapeutic markers in lymphatic filariasis.

Authors:  Vandana Dixit; A K Gupta; P S Bisen; G B K S Prasad; B C Harinath
Journal:  J Clin Lab Anal       Date:  2007       Impact factor: 2.352

8.  Th1-like antifilarial immune responses predominate in antigen-negative persons.

Authors:  K A Dimock; M L Eberhard; P J Lammie
Journal:  Infect Immun       Date:  1996-08       Impact factor: 3.441

9.  A randomized trial of doxycycline for Mansonella perstans infection.

Authors:  Yaya I Coulibaly; Benoit Dembele; Abdallah A Diallo; Ettie M Lipner; Salif S Doumbia; Siaka Y Coulibaly; Siaka Konate; Dapa A Diallo; Daniel Yalcouye; Joseph Kubofcik; Ogobara K Doumbo; Abdel K Traore; Adama D Keita; Michael P Fay; Sekou F Traore; Thomas B Nutman; Amy D Klion
Journal:  N Engl J Med       Date:  2009-10-08       Impact factor: 91.245

10.  Immunodiagnosis of human lymphatic filariasis: A review.

Authors:  P Suba; S Kaliraj; P K Jayaraman; R B Narayanan
Journal:  Indian J Clin Biochem       Date:  1997-12
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