Literature DB >> 8011535

Virus-associated haemophagocytic syndrome: further evidence for a T-cell mediated disorder.

H G Watson1, N J Goulden, L M Manson, G McDermid, J A Gray, A C Parker.   

Abstract

A 16-year-old youth with life-threatening virus-associated haemophagocytic syndrome (VAHS) responded remarkably to treatment with cyclosporin A during two periods of active disease, the second of which was due to noncompliance with treatment. Our clinical observations support the hypothesis that VAHS is cytokine driven as a result of an aberrant T-cell response to infection.

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Year:  1994        PMID: 8011535     DOI: 10.1111/j.1365-2141.1994.tb03282.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN: 0007-1048            Impact factor:   6.998


  2 in total

1.  Successful treatment of non-familial haemophagocytic lymphohistiocytosis with interferon and gammaglobulin.

Authors:  E J Estlin; R D Palmer; K P Windebank; M F Lowry; A D Pearson
Journal:  Arch Dis Child       Date:  1996-11       Impact factor: 3.791

2.  Histiocytic haemophagocytosis in a patient with Kawasaki disease: changes in the hypercytokinaemic state.

Authors:  S Ohga; A Ooshima; J Fukushige; K Ueda
Journal:  Eur J Pediatr       Date:  1995-07       Impact factor: 3.183

  2 in total

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