OBJECTIVE: To determine sociodemographic risk factors associated with HIV-1 infection in a rural Ugandan population. DESIGN: A population-based survey. METHODS: All adult residents (aged > or = 13 years) in a cluster of 15 neighbouring villages of the Masaka District of south-west Uganda were invited to participate in a sociodemographic and serological survey. Questions relating to sexual behaviour were asked separately in an accompanying case-control study. Socioeconomic data and an unambiguous HIV-1 serostatus were obtained by house-to-house survey for 3809 (72%) of the adult population. The association between serostatus and the following variables were analysed: age, sex, marital status, tribe, religion, education, occupational group, place and frequency of travel and recent history of sexually transmitted disease. RESULTS: Women aged 13-21 years were at a much higher risk than men of the same age [odds ratio (OR), 8.6; 95% confidence interval (CI), 3.0-24.5]. Married people aged < 25 years were twice as likely to be infected as those who were not currently married (OR, 2.3; 95% CI, 1.5-3.7). In contrast, in those aged > or = 25 years, women were at a lower risk than men (OR, 0.72; 95% CI, 0.52-0.98) as were those who were currently married compared with those who were not (OR, 0.47; 95% CI, 0.34-0.64). In both age groups those with a history of a recent genital ulcer were approximately three times more likely to be infected. Muslims had lower risks than non-Muslims (OR, 0.58 for both age groups). CONCLUSIONS: The people most at risk of HIV-1 infection in this rural Ugandan population are young married women who had, presumably, commenced sexual activity recently.
OBJECTIVE: To determine sociodemographic risk factors associated with HIV-1 infection in a rural Ugandan population. DESIGN: A population-based survey. METHODS: All adult residents (aged > or = 13 years) in a cluster of 15 neighbouring villages of the Masaka District of south-west Uganda were invited to participate in a sociodemographic and serological survey. Questions relating to sexual behaviour were asked separately in an accompanying case-control study. Socioeconomic data and an unambiguous HIV-1 serostatus were obtained by house-to-house survey for 3809 (72%) of the adult population. The association between serostatus and the following variables were analysed: age, sex, marital status, tribe, religion, education, occupational group, place and frequency of travel and recent history of sexually transmitted disease. RESULTS:Women aged 13-21 years were at a much higher risk than men of the same age [odds ratio (OR), 8.6; 95% confidence interval (CI), 3.0-24.5]. Married people aged < 25 years were twice as likely to be infected as those who were not currently married (OR, 2.3; 95% CI, 1.5-3.7). In contrast, in those aged > or = 25 years, women were at a lower risk than men (OR, 0.72; 95% CI, 0.52-0.98) as were those who were currently married compared with those who were not (OR, 0.47; 95% CI, 0.34-0.64). In both age groups those with a history of a recent genital ulcer were approximately three times more likely to be infected. Muslims had lower risks than non-Muslims (OR, 0.58 for both age groups). CONCLUSIONS: The people most at risk of HIV-1 infection in this rural Ugandan population are young married women who had, presumably, commenced sexual activity recently.
Entities:
Keywords:
Africa; Africa South Of The Sahara; Biology; Demographic Factors; Developing Countries; Diseases; Eastern Africa; Economic Factors; English Speaking Africa; Examinations And Diagnoses; Hiv Infections; Laboratory Examinations And Diagnoses; Population; Population Characteristics; Research Report; Risk Factors; Rural Population; Socioeconomic Factors; Uganda; Viral Diseases
Authors: J W Dorigo-Zetsma; D Belewu; H Meless; E Sanders; R A Coutinho; A Schaap; D Wolday Journal: Sex Transm Infect Date: 2004-04 Impact factor: 3.519
Authors: Hyun J Lim; Alphonse Okwera; Harriet Mayanja-Kizza; Jerrold J Ellner; Roy D Mugerwa; Christopher C Whalen Journal: HIV Clin Trials Date: 2006 Jul-Aug
Authors: Fred Nalugoda; David Guwatudde; John B Bwaninka; Fredrick E Makumbi; Tom Lutalo; Joseph Kagaayi; Nelson K Sewankambo; Godfrey Kigozi; David M Serwadda; Xiangrong Kong; Maria J Wawer; Fred Wabwire-Mangen; Ronald H Gray Journal: J Acquir Immune Defic Syndr Date: 2014-01-01 Impact factor: 3.731
Authors: Eric Lugada; Debra Millar; John Haskew; Mark Grabowsky; Navneet Garg; Mikkel Vestergaard; James G Kahn; James G Khan; James Kahn; Nicholas Muraguri; Jonathan Mermin Journal: PLoS One Date: 2010-08-26 Impact factor: 3.240
Authors: Christine L Mattson; Robert C Bailey; Kawango Agot; J O Ndinya-Achola; Stephen Moses Journal: Sex Transm Dis Date: 2007-10 Impact factor: 2.830