Literature DB >> 8010972

The characterization of a cyclophilin-type peptidyl prolyl cis-trans-isomerase from the endoplasmic-reticulum lumen.

S Bose1, M Mücke, R B Freedman.   

Abstract

A luminally located peptidyl prolyl cis-trans-isomerase (PPI) has been purified from bovine liver microsomes. It has a molecular mass of 20.6 kDa, and N-terminal sequencing demonstrates strong sequence similarity to the sequences of the cyclophilin B family. The enzyme catalyses the isomerization of the standard proline-containing peptide N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide, as well as the refolding of RNAase T1. Kinetic properties, substrate-specificity data and inhibition by cyclosporin A indicate that it is a cyclophilin-type PPI, consistent with the amino-acid-sequence results.

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Year:  1994        PMID： 8010972      PMCID： PMC1138246          DOI： 10.1042/bj3000871

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  30 in total

1.  Folding of ribonuclease T1. 2. Kinetic models for the folding and unfolding reactions.

Authors:  T Kiefhaber; R Quaas; U Hahn; F X Schmid
Journal:  Biochemistry       Date:  1990-03-27       Impact factor: 3.162

2.  Folding of ribonuclease T1. 1. Existence of multiple unfolded states created by proline isomerization.

Authors:  T Kiefhaber; R Quaas; U Hahn; F X Schmid
Journal:  Biochemistry       Date:  1990-03-27       Impact factor: 3.162

3.  Identification and partial purification of ABGP205, an integral membrane glycoprotein from brain that binds ankyrin.

Authors:  K J Treharne; D Rayner; A J Baines
Journal:  Biochem J       Date:  1988-07-15       Impact factor: 3.857

4.  Peptidyl prolyl cis-trans-isomerase activity associated with the lumen of the endoplasmic reticulum.

Authors:  S Bose; R B Freedman
Journal:  Biochem J       Date:  1994-06-15       Impact factor: 3.857

5.  A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin.

Authors:  J J Siekierka; S H Hung; M Poe; C S Lin; N H Sigal
Journal:  Nature       Date:  1989-10-26       Impact factor: 49.962

6.  Isolation and amino acid sequence of cyclophilin.

Authors:  M W Harding; R E Handschumacher; D W Speicher
Journal:  J Biol Chem       Date:  1986-06-25       Impact factor: 5.157

7.  Cyclophilin: a specific cytosolic binding protein for cyclosporin A.

Authors:  R E Handschumacher; M W Harding; J Rice; R J Drugge; D W Speicher
Journal:  Science       Date:  1984-11-02       Impact factor: 47.728

8.  Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins.

Authors:  G Fischer; B Wittmann-Liebold; K Lang; T Kiefhaber; F X Schmid
Journal:  Nature       Date:  1989-02-02       Impact factor: 49.962

9.  Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin.

Authors:  N Takahashi; T Hayano; M Suzuki
Journal:  Nature       Date:  1989-02-02       Impact factor: 49.962

10.  Molecular cloning of the beta-subunit of human prolyl 4-hydroxylase. This subunit and protein disulphide isomerase are products of the same gene.

Authors:  T Pihlajaniemi; T Helaakoski; K Tasanen; R Myllylä; M L Huhtala; J Koivu; K I Kivirikko
Journal:  EMBO J       Date:  1987-03       Impact factor: 11.598
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  11 in total

1.  Protein folding in the secretory pathway of animal cells.

Authors:  R B Freedman; C Greenall; N Jenkins; M F Tuite
Journal:  Cytotechnology       Date:  1995-01       Impact factor: 2.058

2.  A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins.

Authors:  Laurent Meunier; Young-Kwang Usherwood; Kyung Tae Chung; Linda M Hendershot
Journal:  Mol Biol Cell       Date:  2002-12       Impact factor: 4.138

3.  Peptidyl prolyl cis-trans-isomerase activity associated with the lumen of the endoplasmic reticulum.

Authors:  S Bose; R B Freedman
Journal:  Biochem J       Date:  1994-06-15       Impact factor: 3.857

4.  Detailed characterization of a cyclophilin from the human malaria parasite Plasmodium falciparum.

Authors:  M Berriman; A H Fairlamb
Journal:  Biochem J       Date:  1998-09-01       Impact factor: 3.857

5.  A cyclophilin from the polycentric anaerobic rumen fungus Orpinomyces sp. strain PC-2 is highly homologous to vertebrate cyclophilin B.

Authors:  H Chen; X L Li; L G Ljungdahl
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-28       Impact factor: 11.205

6.  Purification and characterization of cytosolic and microsomal cyclophilins from maize (Zea mays).

Authors:  P S Sheldon; M A Venis
Journal:  Biochem J       Date:  1996-05-01       Impact factor: 3.857

7.  Keratinocyte secretion of cyclophilin B via the constitutive pathway is regulated through its cyclosporin-binding site.

Authors:  Paula Fearon; Ann A Lonsdale-Eccles; O Kehinde Ross; Carole Todd; Aparna Sinha; Fabrice Allain; Nick J Reynolds
Journal:  J Invest Dermatol       Date:  2011-01-27       Impact factor: 8.551

8.  Secretion of VEGF-165 has unique characteristics, including shedding from the plasma membrane.

Authors:  Maria Luisa Guzmán-Hernández; Gael Potter; Kristóf Egervári; Jozsef Z Kiss; Tamas Balla
Journal:  Mol Biol Cell       Date:  2014-02-05       Impact factor: 4.138

9.  The cyclophilin inhibitor SCY-635 disrupts hepatitis C virus NS5A-cyclophilin A complexes.

Authors:  Sam Hopkins; Michael Bobardt; Udayan Chatterji; Jose A Garcia-Rivera; Precious Lim; Philippe A Gallay
Journal:  Antimicrob Agents Chemother       Date:  2012-05-14       Impact factor: 5.191

10.  Identification and comparative analysis of the peptidyl-prolyl cis/trans isomerase repertoires of H. sapiens, D. melanogaster, C. elegans, S. cerevisiae and Sz. pombe.

Authors:  Trevor J Pemberton; John E Kay
Journal:  Comp Funct Genomics       Date:  2005
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