| Literature DB >> 8008172 |
J G Piper1, K A Follett, A Fantin.
Abstract
A causal relationship between sex steroids and meningioma proliferation has long been suspected. We report a case of the clinical progression of a sphenoid wing meningioma after the placement of Norplant, a subcutaneous contraceptive implant containing levonorgestrel, a progesterone agonist. Although not proof of causation, this observation lends further credence to the importance of progesterone receptors in the growth and possible treatment of meningiomas.Entities:
Keywords: Americas; Biology; Case Histories; Contraception; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Agents, Progestin; Contraceptive Implants; Contraceptive Methods; Developed Countries; Diseases; Endocrine System; Family Planning; Hormone Receptors; Hormones; Iowa; Levonorgestrel; Membrane Proteins; Neoplasms; North America; Northern America; Ophthalmological Effects; Physiology; Progestational Hormones; Progesterone; United States
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Year: 1994 PMID： 8008172 DOI： 10.1227/00006123-199404000-00022
Source DB: PubMed Journal: Neurosurgery ISSN： 0148-396X Impact factor: 4.654