Literature DB >> 8007764

Effect of metallothionein I on mitochondrial oxygen consumption.

C O Simpkins1, H L Zhao, C A Torrence.   

Abstract

The effect of the stress-induced, cysteine-rich protein, metallothionein I (MT), on oxygen consumption by rat liver mitochondria was studied. Using a Clark-type oxygen electrode we found that electron transport from succinate to oxygen was enhanced by MT whereas ADP-initiated oxygen consumption was inhibited by MT. The MT effect was concentration dependent. No evidence was found for the provision by MT of an alternate pathway to oxygen.

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Year:  1994        PMID: 8007764     DOI: 10.1016/0024-3205(94)00883-3

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  2 in total

1.  Zinc metallothionein imported into liver mitochondria modulates respiration.

Authors:  B Ye; W Maret; B L Vallee
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-13       Impact factor: 11.205

2.  Metallothionein isoform 2A expression is inducible and protects against ROS-mediated cell death in rotenone-treated HeLa cells.

Authors:  Fimmie Reinecke; Oksana Levanets; Yolanda Olivier; Roan Louw; Boitumelo Semete; Anne Grobler; Juan Hidalgo; Jan Smeitink; Antonel Olckers; Francois H Van der Westhuizen
Journal:  Biochem J       Date:  2006-04-15       Impact factor: 3.857

  2 in total

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