Literature DB >> 8004717

Stereochemistry of hydrogen addition to C-25 of desmosterol by sterol-delta 24-reductase of rat liver homogenate.

T Yagi1, N Kobayashi, M Morisaki, N Hara, Y Fujimoto.   

Abstract

Chemically synthesized (26)- and (27)-methyl-13C-labeled desmosterol (3, 5) were separately incubated with rat liver homogenate. 13C-NMR analysis of the incubation products indicated that the C-25 hydrogen of cholesterol was introduced from the si-face of 3 and the re-face of 5.

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Year:  1994        PMID: 8004717     DOI: 10.1248/cpb.42.680

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  1 in total

1.  Biosynthesis of sterols and ecdysteroids in Ajuga hairy roots.

Authors:  Y Fujimoto; K Ohyama; K Nomura; R Hyodo; K Takahashi; J Yamada; M Morisaki
Journal:  Lipids       Date:  2000-03       Impact factor: 1.880

  1 in total

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