| Literature DB >> 800384 |
L G Kiloh, S E Williams, D A Grant, P S Whetton.
Abstract
A double-blind comparative trial of loxapine and trifluoperazine was carried out in 57 acute and chronic schizophrenic patients. In both groups of patients loxapine proved to be equivalent in its effects to trifluoperazine and there were suggestions it might be rather more effective in chronic patients. Side-effects were similar with the two drugs but anticholinergic effects, excitement, dizziness and faintness occurred rather more commonly with loxapine. Laboratory tests, urine analysis, cardiovascular and ophthalmological investigations showed no significant abnormalities.Entities:
Mesh:
Substances:
Year: 1976 PMID: 800384 DOI: 10.1177/030006057600400611
Source DB: PubMed Journal: J Int Med Res ISSN: 0300-0605 Impact factor: 1.671