Literature DB >> 7999131

Molecular cloning of human cytosolic purine 5'-nucleotidase.

J Oka1, A Matsumoto, Y Hosokawa, S Inoue.   

Abstract

The cDNA of human cytosolic purine 5'-nucleotidase (EC 3.1.3.5), which is the supposed regulatory allosteric enzyme of purine nucleotide degradation, has been cloned from a human placenta cDNA library. The predicted open reading fram encodes a protein of 561 amino acids with a molecular mass of 64,966 Da. The deduced amino acid sequence exhibits 95% identity with the sequence of the B type subunit of chicken cytosolic purine 5'-nucleotidase. Northern blot analysis of human placenta poly(A) +RNA revealed a single band of 3.6 kilobases using the cloned cDNA.

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Year:  1994        PMID： 7999131     DOI： 10.1006/bbrc.1994.2752

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  9 in total

1.  Mechanism of the reaction catalysed by cytosolic 5'-nucleotidase/phosphotransferase: formation of a phosphorylated intermediate.

Authors:  C Baiocchi; R Pesi; M Camici; R Itoh; M Grazi Tozzi
Journal:  Biochem J       Date:  1996-08-01       Impact factor: 3.857

2.  Bovine cytosolic IMP/GMP-specific 5'-nucleotidase: cloning and expression of active enzyme in Escherichia coli.

Authors:  S Allegrini; R Pesi; M G Tozzi; C J Fiol; R B Johnson; S Eriksson
Journal:  Biochem J       Date:  1997-12-01       Impact factor: 3.857

3.  The common viral insertion site Evi12 is located in the 5'-noncoding region of Gnn, a novel gene with enhanced expression in two subclasses of human acute myeloid leukemia.

Authors:  Eric van den Akker; Yolanda Vankan-Berkhoudt; Peter J M Valk; Bob Löwenberg; Ruud Delwel
Journal:  J Virol       Date:  2005-05       Impact factor: 5.103

4.  Phosphorylation of ribavirin and viramidine by adenosine kinase and cytosolic 5'-nucleotidase II: Implications for ribavirin metabolism in erythrocytes.

Authors:  Jim Zhen Wu; Gary Larson; Heli Walker; Jae Hoon Shim; Zhi Hong
Journal:  Antimicrob Agents Chemother       Date:  2005-06       Impact factor: 5.191

5.  Guanosine primes acute myeloid leukemia for differentiation via guanine nucleotide salvage synthesis.

Authors:  Hanying Wang; Xin He; Zheng Li; Hongchuan Jin; Xian Wang; Ling Li
Journal:  Am J Cancer Res       Date:  2022-01-15       Impact factor: 6.166

6.  Structure-activity relationship of cytoplasmic 5'-nucleotidase substrate sites.

Authors:  A C Skladanowski; C Hoffmann; J Krass; B Jastorff; W Makarewicz
Journal:  Biochem J       Date:  1996-03-15       Impact factor: 3.857

7.  Integrated Analysis of Summary Statistics to Identify Pleiotropic Genes and Pathways for the Comorbidity of Schizophrenia and Cardiometabolic Disease.

Authors:  Hao Liu; Yang Sun; Xinxin Zhang; Shiyang Li; Dong Hu; Lei Xiao; Yanghui Chen; Lin He; Dao Wen Wang
Journal:  Front Psychiatry       Date:  2020-04-17       Impact factor: 4.157

8.  Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.

Authors:  Gannie Tzoneva; Arianne Perez-Garcia; Zachary Carpenter; Hossein Khiabanian; Valeria Tosello; Maddalena Allegretta; Elisabeth Paietta; Janis Racevskis; Jacob M Rowe; Martin S Tallman; Maddalena Paganin; Giuseppe Basso; Jana Hof; Renate Kirschner-Schwabe; Teresa Palomero; Raul Rabadan; Adolfo Ferrando
Journal:  Nat Med       Date:  2013-02-03       Impact factor: 53.440

9.  Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia.

Authors:  Aleš Hnízda; Jana Škerlová; Milan Fábry; Petr Pachl; Martina Šinalová; Lukáš Vrzal; Petr Man; Petr Novák; Pavlína Řezáčová; Václav Veverka
Journal:  BMC Biol       Date:  2016-10-19       Impact factor: 7.431
  9 in total

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