Literature DB >> 7997520

Free radical-induced double base lesions.

H C Box1, H G Freund, E E Budzinski, J C Wallace, A E Maccubbin.   

Abstract

Evidence is presented for the formation of products in irradiated dinucleoside monophosphates in which both bases are damaged. The dinucleoside monophosphates d(GpT), d(GpC), d(TpG) and d(CpG) were X-irradiated in oxygenated aqueous solution. Product identification was by NMR spectroscopy. In products containing double base lesions, guanine is converted to 8-hydroxyguanine and the pyrimidine base is degraded to a formamido remnant.

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Year:  1995        PMID： 7997520

Source DB:  PubMed          Journal:  Radiat Res        ISSN： 0033-7587            Impact factor:   2.841


  13 in total

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Authors:  Tapas K Hazra; Aditi Das; Soumita Das; Sujata Choudhury; Yoke W Kow; Rabindra Roy
Journal:  DNA Repair (Amst)       Date:  2006-11-20

Review 2.  Formation and repair of oxidatively generated damage in cellular DNA.

Authors:  Jean Cadet; Kelvin J A Davies; Marisa Hg Medeiros; Paolo Di Mascio; J Richard Wagner
Journal:  Free Radic Biol Med       Date:  2017-01-02       Impact factor: 7.376

3.  Oxidatively Damaged DNA: A Possible Antigenic Stimulus for Cancer Autoantibodies.

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Review 4.  Radiation-mediated formation of complex damage to DNA: a chemical aspect overview.

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Journal:  Br J Radiol       Date:  2014-03       Impact factor: 3.039

5.  HO* radicals induce an unexpected high proportion of tandem base lesions refractory to repair by DNA glycosylases.

Authors:  François Bergeron; Frédéric Auvré; J Pablo Radicella; Jean-Luc Ravanat
Journal:  Proc Natl Acad Sci U S A       Date:  2010-03-08       Impact factor: 11.205

Review 6.  Formation and processing of DNA damage substrates for the hNEIL enzymes.

Authors:  Aaron M Fleming; Cynthia J Burrows
Journal:  Free Radic Biol Med       Date:  2016-11-20       Impact factor: 7.376

Review 7.  Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer.

Authors:  H Wiseman; B Halliwell
Journal:  Biochem J       Date:  1996-01-01       Impact factor: 3.857

8.  Enzymatic processing of DNA containing tandem dihydrouracil by endonucleases III and VIII.

Authors:  R Venkhataraman; C D Donald; R Roy; H J You; P W Doetsch; Y W Kow
Journal:  Nucleic Acids Res       Date:  2001-01-15       Impact factor: 16.971

9.  Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG-->TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells.

Authors:  Dong-Hyun Lee; Timothy R O'Connor; Gerd P Pfeifer
Journal:  Nucleic Acids Res       Date:  2002-08-15       Impact factor: 16.971

10.  DNA tandem lesion repair by strand displacement synthesis and nucleotide excision repair.

Authors:  Shuhei Imoto; Leslie A Bransfield; Deborah L Croteau; Bennett Van Houten; Marc M Greenberg
Journal:  Biochemistry       Date:  2008-03-15       Impact factor: 3.162
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