Literature DB >> 7996547

Inhibition of myeloperoxidase release from rat polymorphonuclear leukocytes by a series of azachalcone derivatives.

M L Edwards1, D M Stemerick, J S Sabol, K A Diekema, R J Dinerstein.   

Abstract

A series of azachalcones was evaluated for ability to affect secretion of myeloperoxidase by rat polymorphonuclear leukocytes stimulated by fMLP. The compounds were found to interfere with cellular uptake of extracellular calcium. Structure-activity relationships are discussed.

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Year:  1994        PMID: 7996547     DOI: 10.1021/jm00051a013

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


  1 in total

1.  Photodimerizations of hydroxy- and benzoylated 4-azachalcones and quantum chemical investigation of the reactions.

Authors:  Ahmet Yaşar; Nuran Yayli; Asu Usta; Nurettin Yayli
Journal:  J Mol Model       Date:  2010-02-06       Impact factor: 1.810

  1 in total

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