[Detection and clinical significance of PPD-IgG antibody in cerebrospinal fluid by ABC-ELISA method].

PPD-IgG antibody in cerebrospinal fluid (CSF) of 55 patients with tuberculous meningitis (TBM) and 37 patients with non-TBM was determined by ABC-ELISA method, and compared with ELISA. The positive rate of ABC-ELISA and ELISA was 96.4% and 83.6% respectively (P < 0.05). Specificity of two methods was 97.3%. Meanwhile the positive rate in CSF (96.4%) is markedly higher than that in sera (85.5%) (P < 0.05). The results showed that this method can be as a supporting method for diagnosis of TBM.