BACKGROUND: Neuroimaging of a treatment-resistant patient with schizophrenia revealed the existence of cerebral hemiatrophy. The association of schizophrenia with cerebral hemiatrophy has not previously been reported. RESULTS: Neuroimaging with X-ray computerised tomography showed marked reduction in the volume of the left cerebral hemisphere with secondary enlargement of the left lateral fissure and cortical sulci. High resolution cranial single-photon emission computerised tomography showed a functional deficit of the regional cerebral blood flow in the left lateral parietal and left temporal lobes. CONCLUSIONS: Cerebral hemiatrophy may belong to the lengthening list of neurodevelopmental cerebral anomalies associated with schizophrenia.
BACKGROUND: Neuroimaging of a treatment-resistant patient with schizophrenia revealed the existence of cerebral hemiatrophy. The association of schizophrenia with cerebral hemiatrophy has not previously been reported. RESULTS: Neuroimaging with X-ray computerised tomography showed marked reduction in the volume of the left cerebral hemisphere with secondary enlargement of the left lateral fissure and cortical sulci. High resolution cranial single-photon emission computerised tomography showed a functional deficit of the regional cerebral blood flow in the left lateral parietal and left temporal lobes. CONCLUSIONS:Cerebral hemiatrophy may belong to the lengthening list of neurodevelopmental cerebral anomalies associated with schizophrenia.
Authors: Eva Reiter; Beatrice Heim; Christoph Scherfler; Christoph Mueller; Michael Nocker; Jean-Pierre Ndayisaba; Wolfgang Loescher; Klaus Seppi; Andrew J Lees; Thomas Warner; Werner Poewe; Gregor K Wenning; Atbin Djamshidian Journal: Mov Disord Clin Pract Date: 2016-01-18