Literature DB >> 7994419

Diaspirin crosslinked hemoglobin (DCLHb) polymerization.

T T Hai1, D Nelson, D Pereira, A Srnak.   

Abstract

By employing proprietary polymerization agents possessing specific binding groups and by completing diaspirin crosslinked hemoglobin (DCLHb) polymerization under specific conditions, we have selectively achieved the following objectives: (1) the P50 was adjusted to the physiologic range or left- or right-shifted; (2) the surface of DCLHb was modified ("decorated"); (3) DCLHb was polymerized but not decorated; (4) DCLHb was polymerized and decorated; or (5) DCLHb was site-specifically modified and polymerized.

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Year:  1994        PMID: 7994419     DOI: 10.3109/10731199409117931

Source DB:  PubMed          Journal:  Artif Cells Blood Substit Immobil Biotechnol        ISSN: 1073-1199


  1 in total

1.  Pro-oxidant effects of cross-linked haemoglobins explored using liposome and cytochrome c oxidase vesicle model membranes.

Authors:  M S Rogers; R P Patel; B J Reeder; P Sarti; M T Wilson; A I Alayash
Journal:  Biochem J       Date:  1995-09-15       Impact factor: 3.857

  1 in total

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