| Literature DB >> 7990501 |
A B Pomilio1, G A Solá, A M Mayer, L S Rumi.
Abstract
An in vivo antitumor screening of extracts of Gomphrena martiana indicated positive activity in the petroleum ether extract, and its further bioactivity-directed fractionation resulted in a lipophilic flavonoid fraction. Upon inoculation of various doses of 5,6,7-trisubstituted flavones on two murine tumor lines, Sarcoma 180 and Ehrlich's carcinoma, a decrease of tumor growth was observed. An in vitro KB cultured cell screen indicated cytotoxicity.Entities:
Mesh：
Substances：
Year: 1994 PMID： 7990501 DOI： 10.1016/0378-8741(94)90095-7
Source DB: PubMed Journal: J Ethnopharmacol ISSN： 0378-8741 Impact factor: 4.360