Literature DB >> 7988704

Transient induction of fatty acid synthase in rat liver after removal of a peroxisome proliferator.

K Motojima1, M Isaka, Y Takino, S Goto.   

Abstract

Removal of a peroxisome proliferator from the diet triggered the degradation of peroxisomes and induced the transient expression of a 220 kDa soluble protein in rat liver. The 220 kDa protein was purified by conventional methods and analyzed by amino acid sequencing. A total of 99 amino acid residues in 4 lysylendopeptidase-digested peptides completely matched those in rat fatty acid synthase. The transient induction of fatty acid synthase mRNA during peroxisome degradation was confirmed by Northern blotting.

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Year:  1994        PMID: 7988704     DOI: 10.1016/0014-5793(94)01250-4

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  1 in total

1.  Differential regulation by a peroxisome proliferator of the different multifunctional proteins in guinea pig: cDNA cloning of the guinea pig D-specific multifunctional protein 2.

Authors:  F Caira; M C Clémencet; M Cherkaoui-Malki; M Dieuaide-Noubhani; C Pacot; P P Van Veldhoven; N Latruffe
Journal:  Biochem J       Date:  1998-03-15       Impact factor: 3.857

  1 in total

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