| Literature DB >> 7986688 |
H K Christensen1, K Thomsen, G L Vejlsgaard.
Abstract
Forty-one patients with lymphomatoid papulosis have been followed from 1 to 22 years (mean 11.4 years, median 10 years). Six patients developed malignant lymphoma, 3 cutaneous T-cell lymphoma, 2 Ki-1 large cell lymphoma, and 1 Hodgkin's disease. A clinical malignant presentation combined with the finding of aneuploidy in skin lesions seem to be indications of a malignant potential. Treatment with methotrexate in low dosage is an efficient treatment of lymphomatoid papulosis and probably diminishes the risk of malignancy.Entities:
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Year: 1994 PMID: 7986688
Source DB: PubMed Journal: Semin Dermatol ISSN: 0278-145X