Literature DB >> 7986024

Bactericidal activities of DU-6859a and clinafloxacin (CI-960) against staphylococci.

G J Forstall1, C C Knapp, J A Washington.   

Abstract

Time killing curves were calculated at concentrations of 2 and 8 times the MICs of DU-6859a and clinafloxacin against six isolates of Staphylococcus aureus. Both quinolones produced a decrease in the log10 CFU per milliliter of > or = 3 within 3 h at 2 and 8 times the MIC for the ciprofloxacin-susceptible isolates and at 8 times the MIC for the ciprofloxacin-resistant isolates; however, only 8 times the MIC of DU-6859a consistently prevented regrowth of all isolates after 24 h of incubation.

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Year:  1994        PMID： 7986024      PMCID： PMC284653          DOI： 10.1128/AAC.38.8.1868

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

1.  Effect of antibiotics carry-over on bacterial counting by 'spiral plating'.

Authors:  E Yourassowsky; M P Van der Linden; F Crokaert; Y Glupczynski
Journal:  J Antimicrob Chemother       Date:  1988-01       Impact factor: 5.790

2.  Protective effect of amdinocillin against emergence of resistance to ceftazidime in Enterobacter cloacae.

Authors:  E Yourassowsky; M P van der Linden; M J Lismont; F Crokaert; Y Glupczynski
Journal:  Antimicrob Agents Chemother       Date:  1988-11       Impact factor: 5.191

3.  CI-960, a new fluoroquinolone, for therapy of experimental ciprofloxacin-susceptible and -resistant Staphylococcus aureus endocarditis.

Authors:  G W Kaatz; S M Seo; K C Lamp; E M Bailey; M J Rybak
Journal:  Antimicrob Agents Chemother       Date:  1992-06       Impact factor: 5.191

4.  Antimicrobial activity of DU-6859, a new potent fluoroquinolone, against clinical isolates.

Authors:  K Sato; K Hoshino; M Tanaka; I Hayakawa; Y Osada
Journal:  Antimicrob Agents Chemother       Date:  1992-07       Impact factor: 5.191

5.  In vitro antistaphylococcal activities of two investigative fluoroquinolones, CI-960 and WIN 57273, compared with those of ciprofloxacin, mupirocin (pseudomonic acid), and peptide-class antimicrobial agents.

Authors:  K E Aldridge
Journal:  Antimicrob Agents Chemother       Date:  1992-04       Impact factor: 5.191
  5 in total
  2 in total

Review 1.  In vitro activity of fluoroquinolones against gram-positive bacteria.

Authors:  G M Eliopoulos
Journal:  Drugs       Date:  1995       Impact factor: 9.546

2.  Effects of ABCB1, UGT1A1, and UGT1A9 Genetic Polymorphisms on the Pharmacokinetics of Sitafloxacin Granules in Healthy Subjects.

Authors:  Lu-Ning Sun; Guo-Xian Sun; Yu-Qing Yang; Ye Shen; Feng-Ru Huang; Li-Jun Xie; Juan Cheng; Hong-Wen Zhang; Xue-Hui Zhang; Yun Liu; Yong-Qing Wang
Journal:  Clin Pharmacol Drug Dev       Date:  2020-07-20
  2 in total

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