| Literature DB >> 7986013 |
M Lebbadi1, A Gálvez, E Valdivia, M Martínez-Bueno, M Maqueda.
Abstract
Amoebicin m4-A from Bacillus licheniformis M-4 exerts a bactericidal and bacteriolytic action on Bacillus megaterium GR10. Protein, DNA, and RNA synthesis are inhibited, and the membrane electrical potential of this bacterium is depleted by amoebicin. Synthesis of DNA and RNA by Naegleria fowleri HB-1 is also inhibited. Liposomes constructed from L-alpha-phosphatidylcholine become permeable to ions, low-molecular-weight solutes, and high-molecular-weight polymers after treatment with amoebicin.Entities:
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Year: 1994 PMID: 7986013 PMCID: PMC284642 DOI: 10.1128/AAC.38.8.1820
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191