Literature DB >> 7981028

Cell reproduction: induction of M-phase events by cyclin-dependent cdc2 kinase.

T Kishimoto1.   

Abstract

Although a major concern in the development of multicellular organisms is cell differentiation, the construction of a multicellular system essentially depends on cell multiplication, which consists of genomic duplication and segregation. Recent progress has revealed that cyclin-dependent kinases (CDKs) are key components of a cell cycle engine that governs cell proliferation. This article focuses on how CDKs induce M-phase events characterized by nuclear membrane breakdown, chromosome condensation and mitotic spindle formation to assure genomic segregation.

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Year:  1994        PMID： 7981028

Source DB:  PubMed          Journal:  Int J Dev Biol        ISSN： 0214-6282            Impact factor:   2.203


  6 in total

1.  Cell cycle in the fucus zygote parallels a somatic cell cycle but displays a unique translational regulation of cyclin-dependent kinases.

Authors:  F Corellou; C Brownlee; L Detivaud; B Kloareg; F Y Bouget
Journal:  Plant Cell       Date:  2001-03       Impact factor: 11.277

2.  Actopaxin is phosphorylated during mitosis and is a substrate for cyclin B1/cdc2 kinase.

Authors:  Michael Curtis; Sotiris N Nikolopoulos; Christopher E Turner
Journal:  Biochem J       Date:  2002-04-15       Impact factor: 3.857

3.  The H1 phosphorylation state regulates expression of CDC2 and other genes in response to starvation in Tetrahymena thermophila.

Authors:  Yali Dou; Xiaoyuan Song; Yifan Liu; Martin A Gorovsky
Journal:  Mol Cell Biol       Date:  2005-05       Impact factor: 4.272

4.  14-3-3 σ expression effects G2/M response to oxygen and correlates with ovarian cancer metastasis.

Authors:  Dashnamoorthy Ravi; Yidong Chen; Bijal Karia; Adam Brown; Ting Ting Gu; Jie Li; Mark S Carey; Bryan T Hennessy; Alexander J R Bishop
Journal:  PLoS One       Date:  2011-01-10       Impact factor: 3.240

5.  Initial triggering of M-phase in starfish oocytes: a possible novel component of maturation-promoting factor besides cdc2 kinase.

Authors:  E Okumura; T Sekiai; S Hisanaga; K Tachibana; T Kishimoto
Journal:  J Cell Biol       Date:  1996-01       Impact factor: 10.539

6.  Cyclin B interaction with microtubule-associated protein 4 (MAP4) targets p34cdc2 kinase to microtubules and is a potential regulator of M-phase microtubule dynamics.

Authors:  K Ookata; S Hisanaga; J C Bulinski; H Murofushi; H Aizawa; T J Itoh; H Hotani; E Okumura; K Tachibana; T Kishimoto
Journal:  J Cell Biol       Date:  1995-03       Impact factor: 10.539
  6 in total

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