| Literature DB >> 79807 |
A W Segal, O T Jones, D Webster, A C Allison.
Abstract
A unique cytochrome b which becomes incorporated into phagocytic vacuoles has been described in human neutrophils. This cytochrome b appears to be situated in the plasma membrane of these cells, and acts as a component of the microbicidal oxidase system. Absence or gross abnormality of this cytochrome b was demonstrated in all four patients with chronic granulomatous disease who were investigated, and reduced concentrations in two mothers known to be carriers of the disease.Entities:
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Year: 1978 PMID： 79807 DOI： 10.1016/s0140-6736(78)91445-9
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321