OBJECTIVE: To determine the prevalence of magnetic resonance imaging (MRI) lesions in systemic lupus erythematosus (SLE) patients without a history of neuropsychiatric symptoms and to correlate any MRI abnormalities with the patient's other disease manifestations or treatment. METHODS: Prospective study of 32 consecutive patients with SLE without a history of neuropsychiatric symptoms, from inpatient and outpatient rheumatology services, who underwent MRI scan during a 3-year period. RESULTS: Five patients had MRI abnormalities consisting of white matter lesions or periventricular hyperintensities; this is similar to the prevalence of these abnormalities in the general population. CONCLUSION: The prevalence of silent brain MRI abnormalities is not increased in SLE patients who do not have a history of neuropsychiatric manifestations.
OBJECTIVE: To determine the prevalence of magnetic resonance imaging (MRI) lesions in systemic lupus erythematosus (SLE) patients without a history of neuropsychiatric symptoms and to correlate any MRI abnormalities with the patient's other disease manifestations or treatment. METHODS: Prospective study of 32 consecutive patients with SLE without a history of neuropsychiatric symptoms, from inpatient and outpatient rheumatology services, who underwent MRI scan during a 3-year period. RESULTS: Five patients had MRI abnormalities consisting of white matter lesions or periventricular hyperintensities; this is similar to the prevalence of these abnormalities in the general population. CONCLUSION: The prevalence of silent brain MRI abnormalities is not increased in SLEpatients who do not have a history of neuropsychiatric manifestations.
Authors: Paola C Roldan; Rex E Jung; Wilmer L Sibbitt; Clifford R Qualls; Ranee A Flores; Carlos A Roldan Journal: Rheumatol Int Date: 2018-06-13 Impact factor: 2.631
Authors: Rex E Jung; Judith M Segall; Rachael G Grazioplene; Clifford Qualls; Wilmer L Sibbitt; Carlos A Roldan Journal: PLoS One Date: 2010-03-24 Impact factor: 3.240
Authors: Wilmer L Sibbitt; William M Brooks; Mario Kornfeld; Blaine L Hart; Arthur D Bankhurst; Carlos A Roldan Journal: Semin Arthritis Rheum Date: 2009-10-31 Impact factor: 5.532