M Kohli-Kumar1, J Barbosa, R E Harris. 1. Hematology/Oncology Division, Children's Hospital Medical Center, Cincinnati, OH 45229.
Abstract
PURPOSE: Malignancy of the sphenoid sinus, especially metastatic involvement, is an extremely rare event at any age and is usually associated with a poor prognosis. We present a case of a 5-year-old boy who underwent allogenic bone marrow transplantation for stage IV neuroblastoma. PATIENTS AND METHODS: Three years later, he presented with an isolated lesion, histologically proven to be neuroblastoma, in the sphenoid sinus. RESULTS: Partial excision of the tumor, followed by chemotherapy and radiotherapy, achieved a remission for 3 years.
PURPOSE: Malignancy of the sphenoid sinus, especially metastatic involvement, is an extremely rare event at any age and is usually associated with a poor prognosis. We present a case of a 5-year-old boy who underwent allogenic bone marrow transplantation for stage IV neuroblastoma. PATIENTS AND METHODS: Three years later, he presented with an isolated lesion, histologically proven to be neuroblastoma, in the sphenoid sinus. RESULTS: Partial excision of the tumor, followed by chemotherapy and radiotherapy, achieved a remission for 3 years.