Literature DB >> 7976063

Reaction of the organism to stress: the survival attractor concept.

J Viret1.   

Abstract

This paper outlines a phenomenological approach for describing physiological reactions occurring immediately after vital threats. This exemplified by data taken from previous studies relative to chemical intoxications of rats by a neurotoxical drug. The survival rate of the animals and the variations of their cerebral acetylcholinesterase activity are both reported as a function of the drug concentration, and with respect to their age. The collecting of the results may be described as the cusp, a bifurcation set of Thom's Catastrophe Theory. The young animals react by a vital burst which modifies the shape of the cusp. A new fold or pocket takes place, changing it to the butterfly bifurcation set. This pocket supports the survival attractor concept, which appears reactional, transitory and variable in its intensity. In the last part of the paper, an extension of this concept is proposed to the visual domain. Some of patients who have suddenly and partially lost their visual acuity can recover some visual capacity by developing a new ability to see in weak contrasts. This reaction may be described as a visual survival attractor.

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Year:  1994        PMID: 7976063     DOI: 10.1007/BF00709484

Source DB:  PubMed          Journal:  Acta Biotheor        ISSN: 0001-5342            Impact factor:   1.774


  3 in total

1.  Esterase activities and soman toxicity in developing rat.

Authors:  S H Sterri; G Berge; F Fonnum
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1985-08

2.  Age-related differences in soman toxicity and in blood and brain regional cholinesterase activity.

Authors:  T M Shih; D M Penetar; J H McDonough; J A Romano; J M King
Journal:  Brain Res Bull       Date:  1990-03       Impact factor: 4.077

3.  Rat brain acetylcholinesterase turnover in vivo: use of a radioactive methylphosphonothiate irreversible inhibitor.

Authors:  P Goossens; J Viret; F Leterrier
Journal:  Biochem Biophys Res Commun       Date:  1984-08-30       Impact factor: 3.575

  3 in total
  2 in total

1.  Introducing catastrophe-QSAR. Application on modeling molecular mechanisms of pyridinone derivative-type HIV non-nucleoside reverse transcriptase inhibitors.

Authors:  Mihai V Putz; Marius Lazea; Ana-Maria Putz; Corina Duda-Seiman
Journal:  Int J Mol Sci       Date:  2011-12-20       Impact factor: 5.923

Review 2.  Chemical Structure-Biological Activity Models for Pharmacophores' 3D-Interactions.

Authors:  Mihai V Putz; Corina Duda-Seiman; Daniel Duda-Seiman; Ana-Maria Putz; Iulia Alexandrescu; Maria Mernea; Speranta Avram
Journal:  Int J Mol Sci       Date:  2016-07-08       Impact factor: 5.923

  2 in total

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