Literature DB >> 7974533

Urgent therapy for acute stroke. Effects of a stroke trial on untreated patients.

W G Barsan1, T G Brott, J P Broderick, E C Haley, D E Levy, J R Marler.   

Abstract

BACKGROUND AND
PURPOSE: As part of the recruitment efforts for the National Institutes of Health Tissue Plasminogen Activator Pilot Study, public education and awareness campaigns were conducted to encourage early hospital arrival. We evaluated the change in arrival times during the course of the study for all stroke patients, including those who were not entered into study.
METHODS: Data were gathered on all patients presenting within 24 hours of stroke onset to all of the study hospitals. Coincident with the start of the study, educational and promotional programs, which stressed signs and symptoms of stroke and the need to call 911, were presented to physicians, paramedical personnel, and the public. The study was divided into four quartiles to analyze differences in time to hospital arrival and use of 911.
RESULTS: Of 2099 patients screened, time data were available on 1116. During the course of the study, the mean time from symptom onset to hospital arrival declined significantly (3.2 hours versus 1.5 hours). Patients arrived for treatment sooner at community hospitals than at university/teaching hospitals. The use of 911 increased from 39% in the first quartile of the study to 60% in the fourth quartile. This was a consistent finding in all study sites. Increased use of 911 was seen almost exclusively in patients with nonhemorrhagic stroke.
CONCLUSIONS: Times from stroke onset to hospital arrival decreased significantly during the course of the National Institutes of Health Tissue Plasminogen Activator Pilot Study. Significantly increased use of 911 was the likely major explanation for the shortened arrival times. The decrease in arrival times may be a consequence of the public and professional education programs conducted at all study sites.

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Mesh:

Year:  1994        PMID: 7974533     DOI: 10.1161/01.str.25.11.2132

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


  11 in total

1.  [European Stroke Organisation 2008 guidelines for managing acute cerebral infarction or transient ischemic attack. Part 1].

Authors:  P Ringleb; P D Schellinger; W Hacke
Journal:  Nervenarzt       Date:  2008-08       Impact factor: 1.214

Review 2.  Organization of regional and local stroke resources: methods to expedite acute management of stroke.

Authors:  James Kennedy; Christina Ma; Alastair M Buchan
Journal:  Curr Neurol Neurosci Rep       Date:  2004-01       Impact factor: 5.081

Review 3.  A comprehensive review of prehospital and in-hospital delay times in acute stroke care.

Authors:  K R Evenson; R E Foraker; D L Morris; W D Rosamond
Journal:  Int J Stroke       Date:  2009-06       Impact factor: 5.266

Review 4.  ["Time is brain". Optimizing prehospital stroke management].

Authors:  A Haass; S Walter; A Ragoschke-Schumm; I Q Grunwald; M Lesmeister; A V Khaw; K Fassbender
Journal:  Nervenarzt       Date:  2014-02       Impact factor: 1.214

Review 5.  Systematic review of mass media interventions designed to improve public recognition of stroke symptoms, emergency response and early treatment.

Authors:  Jan Lecouturier; Helen Rodgers; Madeleine J Murtagh; Martin White; Gary A Ford; Richard G Thomson
Journal:  BMC Public Health       Date:  2010-12-23       Impact factor: 3.295

6.  Reducing delay in patients with acute coronary syndrome and other time-critical conditions: a systematic review to identify the behaviour change techniques associated with effective interventions.

Authors:  Barbara Farquharson; Purva Abhyankar; Karen Smith; Stephan U Dombrowski; Shaun Treweek; Nadine Dougall; Brian Williams; Marie Johnston
Journal:  Open Heart       Date:  2019-02-27

7.  Addressing stroke signs and symptoms through public education: the Stroke Heroes Act FAST campaign.

Authors:  Hilary K Wall; Brianne M Beagan; June O'Neill; Kathleen M Foell; Cynthia L Boddie-Willis
Journal:  Prev Chronic Dis       Date:  2008-03-15       Impact factor: 2.830

Review 8.  Stroke warning campaigns: delivering better patient outcomes? A systematic review.

Authors:  Lisa Mellon; Frank Doyle; Daniela Rohde; David Williams; Anne Hickey
Journal:  Patient Relat Outcome Meas       Date:  2015-02-25

9.  Knowledge of thrombolytic therapy for acute ischemic stroke among community residents in western urban China.

Authors:  Juan Yang; Min Zheng; Shuqun Chen; Shu Ou; Jie Zhang; Ni Wang; Yingying Cao; Jian Wang
Journal:  PLoS One       Date:  2014-09-15       Impact factor: 3.240

Review 10.  Translation of the 'time is brain' concept into clinical practice: focus on prehospital stroke management.

Authors:  A Ragoschke-Schumm; S Walter; A Haass; C Balucani; M Lesmeister; A Nasreldein; L Sarlon; A Bachhuber; T Licina; I Q Grunwald; K Fassbender
Journal:  Int J Stroke       Date:  2014-03-04       Impact factor: 5.266

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