Literature DB >> 7973900

Experimental manipulation of cocaine craving by videotaped environmental cues.

M D Kilgus1, A J Pumariega.   

Abstract

Thirteen male patients consecutively admitted to an inpatient drug and alcohol rehabilitation hospital with the primary diagnosis of crack cocaine dependence were shown a 30-minute videotape that included salient environmental cues intended to elicit cocaine craving. The subjects were tested before and after the videotape by the use of a continuous 20-cm analogue visual instrument that asks them to rate their perceived degree of craving, mood, energy, and wellness. Only craving showed a statistically significant change from pretest to posttest. Correlations among the four separate ratings suggest that mood and craving are different dimensions that independently contribute to one's general sense of well-being. This study demonstrates that cocaine craving can be induced in a group setting by presenting certain visual and auditory cues on a video monitor. The procedure of obtaining self-ratings in response to videotaped environmental cues could be easily incorporated into research methods designed to assess pharmacologic efficacy in reducing the intense craving that reinforces addiction.

Entities:  

Mesh:

Substances:

Year:  1994        PMID: 7973900     DOI: 10.1097/00007611-199411000-00016

Source DB:  PubMed          Journal:  South Med J        ISSN: 0038-4348            Impact factor:   0.954


  5 in total

1.  Cocaine deprivation effect: cue abstinence over weekends boosts anticipatory 50-kHz ultrasonic vocalizations in rats.

Authors:  Esther Y Maier; Allison M Ahrens; Sean T Ma; Timothy Schallert; Christine L Duvauchelle
Journal:  Behav Brain Res       Date:  2010-05-12       Impact factor: 3.332

2.  Cocaine-predictive stimulus induces drug-seeking behavior and neural activation in limbic brain regions after multiple months of abstinence: reversal by D(1) antagonists.

Authors:  R Ciccocioppo; P P Sanna; F Weiss
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-13       Impact factor: 11.205

3.  Control of cocaine-seeking behavior by drug-associated stimuli in rats: effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens.

Authors:  F Weiss; C S Maldonado-Vlaar; L H Parsons; T M Kerr; D L Smith; O Ben-Shahar
Journal:  Proc Natl Acad Sci U S A       Date:  2000-04-11       Impact factor: 11.205

4.  Drug addiction: functional neurotoxicity of the brain reward systems.

Authors:  F Weiss; G F Koob
Journal:  Neurotox Res       Date:  2001-01       Impact factor: 3.911

5.  The effects of varied extinction procedures on contingent cue-induced reinstatement in Sprague-Dawley rats.

Authors:  Deanne M Buffalari; Matthew W Feltenstein; Ronald E See
Journal:  Psychopharmacology (Berl)       Date:  2013-06-18       Impact factor: 4.530

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.