Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The comparison of effects of various anesthetics on expression of Fos protein in the rat brain.

Literature DB >> 7970238

The comparison of effects of various anesthetics on expression of Fos protein in the rat brain.

Abstract

The purpose of this study was to compare effects of various anesthetic drugs on expression of Fos protein in the supraspinal neurons of rats. Optimum anesthesia was maintained under monitoring of EEG. Degree of Fos expression was evaluated by counts of Fos-immunoreactive (ir) neurons. Urethane induced the largest amount of Fos-ir neurons (n = 8439), while fentanyl/midazolam the smallest (n = 112). alpha-Chloralose, halothane, pentobarbital sodium and urethane/alpha-chloralose induced amounts in between. The results indicate that fentanyl/midazolam is the most recommendable anesthetic drug in the Fos expression study.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1994 PMID： 7970238 DOI： 10.1016/0304-3940(94)90871-0

Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046

Keyword Cloud
Cited

17 in total

1. Stoichiometry of N-methyl-D-aspartate receptors within the suprachiasmatic nucleus.

Authors: J P Clark; P Kofuji
Journal: J Neurophysiol Date: 2010-04-21 Impact factor: 2.714

2. Local morphine withdrawal increases c-fos gene, Fos protein, and oxytocin gene expression in hypothalamic magnocellular neurosecretory cells.

Authors: L E Johnstone; C H Brown; H K Meeren; C L Vuijst; P J Brooks; G Leng; J A Russell
Journal: J Neurosci Date: 2000-02-01 Impact factor: 6.167

3. Electrically induced static exercise elicits a pressor response in the decerebrate rat.

Authors: S A Smith; J H Mitchell; M G Garry
Journal: J Physiol Date: 2001-12-15 Impact factor: 5.182

4. C-Fos expression in trigeminal nucleus neurons after chemical irritation of the cornea: reduction by selective blockade of nociceptor chemosensitivity.

Authors: S Martinez; C Belmonte
Journal: Exp Brain Res Date: 1996-04 Impact factor: 1.972

5. Antinociceptive action of nitrous oxide is mediated by stimulation of noradrenergic neurons in the brainstem and activation of [alpha]2B adrenoceptors.

Authors: S Sawamura; W S Kingery; M F Davies; G S Agashe; J D Clark; B K Kobilka; T Hashimoto; M Maze
Journal: J Neurosci Date: 2000-12-15 Impact factor: 6.167

The comparison of effects of various anesthetics on expression of Fos protein in the rat brain.

1. Stoichiometry of N-methyl-D-aspartate receptors within the suprachiasmatic nucleus.

2. Local morphine withdrawal increases c-fos gene, Fos protein, and oxytocin gene expression in hypothalamic magnocellular neurosecretory cells.

3. Electrically induced static exercise elicits a pressor response in the decerebrate rat.

4. C-Fos expression in trigeminal nucleus neurons after chemical irritation of the cornea: reduction by selective blockade of nociceptor chemosensitivity.

5. Antinociceptive action of nitrous oxide is mediated by stimulation of noradrenergic neurons in the brainstem and activation of [alpha]2B adrenoceptors.

6. Projection neurons of the vestibulo-sympathetic reflex pathway.

7. CXCR4 receptors in the dorsal medulla: implications for autonomic dysfunction.

8. Cerebral activity during the anesthesia-like state induced by mesopontine microinjection of pentobarbital.

9. c-Fos Expression in the Nucleus of the Solitary Tract in Response to Salt Stimulation in Rats.

10. Activation of brainstem neurons by underwater diving in the rat.