Literature DB >> 7970147

Interleukin-1 beta production during the onset of heat stroke in rabbits.

M T Lin1, T Y Kao, C F Su, S S Hsu.   

Abstract

During the onset of heat stroke, rabbits displayed hyperthermia (42.8 degrees C), decreased arterial blood pressure, increased intracranial pressure, decreased cerebral perfusion pressure and increased interleukin-1 beta production (in both the hypothalamus and plasma), compared to those of normothermic, control rabbits. In addition, the heat-stroke animals which received an i.v. injection of interleukin 1-receptor antagonist (200 micrograms/kg) had a survival time (interval between onset of heat stroke and death) longer than that of the heat-stroke animals which received control-vehicle solution. The data indicate that interleukin-1 production plays a role in pathogenesis of heat stroke in rabbits.

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Year:  1994        PMID: 7970147     DOI: 10.1016/0304-3940(94)90108-2

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  10 in total

1.  Glucocorticoids reduce interleukin-1 concentration and result in neuroprotective effects in rat heatstroke.

Authors:  C C Liu; C H Chien; M T Lin
Journal:  J Physiol       Date:  2000-09-01       Impact factor: 5.182

Review 2.  The roles of exercise-induced immune system disturbances in the pathology of heat stroke : the dual pathway model of heat stroke.

Authors:  Chin Leong Lim; Laurel T Mackinnon
Journal:  Sports Med       Date:  2006       Impact factor: 11.136

3.  Interleukin-1 receptor antagonist restores homeostatic function and limits multiorgan damage in heatstroke.

Authors:  Kun-Hung Shen; Chen-Kuei Chang; Mao-Tsun Lin; Ching-Ping Chang
Journal:  Eur J Appl Physiol       Date:  2008-05-06       Impact factor: 3.078

4.  Effects of hypertonic (3%) saline in rats with circulatory shock and cerebral ischemia after heatstroke.

Authors:  Jinn-Rung Kuo; Chia-Li Lin; Chung-Ching Chio; Jhi-Joung Wang; Mao-Tsun Lin
Journal:  Intensive Care Med       Date:  2003-06-19       Impact factor: 17.440

5.  Ischemic and oxidative damage to the hypothalamus may be responsible for heat stroke.

Authors:  Sheng-Hsien Chen; Mao-Tsun Lin; Ching-Ping Chang
Journal:  Curr Neuropharmacol       Date:  2013-03       Impact factor: 7.363

6.  Chungsim-Yeunja-Tang decreases the inflammatory response in peripheral blood mononuclear cells from patients with cerebral infarction through an NF-κB dependent mechanism.

Authors:  Hyun-Ja Jeong; In-Young Choi; Min-Ho Kim; Hyung-Min Kim; Phil-Dong Moon; Jin-Woo Hong; Soo-Hyun Kim
Journal:  J Neuroinflammation       Date:  2010-11-25       Impact factor: 8.322

7.  Attenuation of circulatory shock and cerebral ischemia injury in heat stroke by combination treatment with dexamethasone and hydroxyethyl starch.

Authors:  Tsai-Hsiu Yang; Mei-Fen Shih; Yi-Szu Wen; Wen-Yueh Ho; Kuen-Lin Leu; Mei-Ying Wang; Chia-Chyuan Liu
Journal:  Exp Transl Stroke Med       Date:  2010-10-11

Review 8.  Mesenchymal stem cell-based treatments for stroke, neural trauma, and heat stroke.

Authors:  Yogi Chang-Yo Hsuan; Cheng-Hsien Lin; Ching-Ping Chang; Mao-Tsun Lin
Journal:  Brain Behav       Date:  2016-08-03       Impact factor: 2.708

9.  The Increase in IL-1β in the Early Stage of Heatstroke Might Be Caused by Splenic Lymphocyte Pyroptosis Induced by mtROS-Mediated Activation of the NLRP3 Inflammasome.

Authors:  Gong Wang; Tingting Shen; Ping Li; Zhen Luo; Yulong Tan; Genlin He; Xiaoliang Zhang; Ju Yang; Jun Liu; Yuan Wang; He Tang; Xue Luo; Xuesen Yang
Journal:  Front Immunol       Date:  2019-12-11       Impact factor: 7.561

10.  Effects of Vitamin C or E on the Pro-inflammatory Cytokines, Heat Shock Protein 70 and Antioxidant Status in Broiler Chicks under Summer Conditions.

Authors:  In-Surk Jang; Young-Hyun Ko; Yang-Soo Moon; Sea-Hwan Sohn
Journal:  Asian-Australas J Anim Sci       Date:  2014-05       Impact factor: 2.509

  10 in total

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