Literature DB >> 7969490

Gene inhibition using antisense oligodeoxynucleotides.

R W Wagner1.   

Abstract

Antisense oligodeoxynucleotides (ODNs) have great promise as agents for the specific manipulation of gene expression. Until recently, nonspecific effects of ODNs often confounded the interpretation of antisense studies. Improvements in ODN chemistry and cellular delivery techniques now allow for more potent and specific gene inhibition. This review critically evaluates recent progress in the development of antisense ODNs.

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Year:  1994        PMID： 7969490     DOI： 10.1038/372333a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  117 in total

1.  Inhibition of IL-6 in mice by anti-NF-kappaB oligodeoxyribonucleotide N3'-->oligodeoxyribonnucleotide N3' --> P5' phosphoramidates.

Authors:  L Wang; S Gryaznov; M Nerenberg
Journal:  Inflammation       Date:  1999-12       Impact factor: 4.092

2.  Target site search and effective inhibition of leukaemic cell growth by a covalently closed multiple anti-sense oligonucleotide to c-myb.

Authors:  I J Moon; Y Lee; C S Kwak; J H Lee; K Choi; A D Schreiber; J G Park
Journal:  Biochem J       Date:  2000-03-01       Impact factor: 3.857

Review 3.  Designing antisense to inhibit the renin-angiotensin system.

Authors:  D Mohuczy; M I Phillips
Journal:  Mol Cell Biochem       Date:  2000-09       Impact factor: 3.396

4.  Inhibitory effects of EGFR antisense oligodeox ynucleotide in human colorectal cancer cell line.

Authors:  Yong He; Jun Zhou; Jin-Sheng Wu; Ke-Feng Dou
Journal:  World J Gastroenterol       Date:  2000-10       Impact factor: 5.742

5.  Gene interference using antisense oligodeoxynucleotides on whole chick embryos. Optimal ring and roller-bottle culture technique.

Authors:  J Cooke; A Isaac
Journal:  Mol Biotechnol       Date:  2000-07       Impact factor: 2.695

6.  Targeted delivery of oligodeoxynucleotides to parenchymal liver cells in vivo.

Authors:  E A Biessen; H Vietsch; E T Rump; K Fluiter; J Kuiper; M K Bijsterbosch; T J van Berkel
Journal:  Biochem J       Date:  1999-06-15       Impact factor: 3.857

Review 7.  DNA-Based Biomaterials for Immunoengineering.

Authors:  Midori Maeda; Taisuke Kojima; Yang Song; Shuichi Takayama
Journal:  Adv Healthc Mater       Date:  2018-12-05       Impact factor: 9.933

8.  Functionally differentiating two neuronal nitric oxide synthase isoforms through antisense mapping: evidence for opposing NO actions on morphine analgesia and tolerance.

Authors:  Y A Kolesnikov; Y X Pan; A M Babey; S Jain; R Wilson; G W Pasternak
Journal:  Proc Natl Acad Sci U S A       Date:  1997-07-22       Impact factor: 11.205

9.  Potent and selective gene inhibition using antisense oligodeoxynucleotides.

Authors:  W M Flanagan; R W Wagner
Journal:  Mol Cell Biochem       Date:  1997-07       Impact factor: 3.396

10.  Inhibition of NF-kappa B-Rel A expression by antisense oligodeoxynucleotides suppresses synthesis of urokinase-type plasminogen activator (uPA) but not its inhibitor PAI-1.

Authors:  U Reuning; O Wilhelm; T Nishiguchi; L Guerrini; F Blasi; H Graeff; M Schmitt
Journal:  Nucleic Acids Res       Date:  1995-10-11       Impact factor: 16.971
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