| Literature DB >> 7967988 |
P Lewis1, S Griffin, P Marsden, T Gee, T Nunan, M Malsey, J Dussek.
Abstract
Despite use of computed tomography, some lung cancer patients are found to have unresectable disease at surgery, or they present early with metastases. We studied whether whole-body positron emission tomography (PET) with 18F-fluorodeoxyglucose (18FDG) would improve the preoperative detection of metastases. We retrospectively analysed 34 patients with "operable" non-small-cell lung cancer who underwent 18FDG PET after routine assessment. Management changes produced by the PET scan and confirmatory tests were reviewed. PET identified unsuspected malignant lesions in 10 (29%) patients. Management changes occurred in 14 (41%), including 6 (18%) patients who were changed to non-surgical therapy. These data suggest that whole-body 18FDG PET improves preoperative assessment of lung cancer patients.Entities:
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Year: 1994 PMID: 7967988 DOI: 10.1016/s0140-6736(94)90753-6
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321