Literature DB >> 7966540

Chagasic meningoencephalitis with detection of Trypanosoma cruzi in the cerebrospinal fluid of an immunodepressed patient.

E Jardim1, O M Takayanagui.   

Abstract

We report a case of chagasic meningoencephalitis with the detection of Trypanosoma cruzi in the cerebrospinal fluid (CSF). The patient was a renal transplant recipient with a chagasic history preceding surgery who had been receiving immunosuppressive medication for 8 years, a probable cause of the recrudescence of Chagas' disease. He was treated with benznidazole, with normalization of the CSF. He was discharged from hospital in a good clinical condition.

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Year:  1994        PMID: 7966540

Source DB:  PubMed          Journal:  J Trop Med Hyg        ISSN: 0022-5304


  4 in total

1.  Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection.

Authors:  V Michailowsky; N M Silva; C D Rocha; L Q Vieira; J Lannes-Vieira; R T Gazzinelli
Journal:  Am J Pathol       Date:  2001-11       Impact factor: 4.307

2.  "Autoimmune rejection" of neonatal heart transplants in experimental Chagas disease is a parasite-specific response to infected host tissue.

Authors:  R L Tarleton; L Zhang; M O Downs
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-15       Impact factor: 11.205

3.  Phenyl-alpha-tert-butyl-nitrone and benzonidazole treatment controlled the mitochondrial oxidative stress and evolution of cardiomyopathy in chronic chagasic Rats.

Authors:  Jian-Jun Wen; Shivali Gupta; Zhangjun Guan; Monisha Dhiman; David Condon; Charles Lui; Nisha Jain Garg
Journal:  J Am Coll Cardiol       Date:  2010-06-01       Impact factor: 24.094

4.  IL-12p40 deficiency leads to uncontrolled Trypanosoma cruzi dissemination in the spinal cord resulting in neuronal death and motor dysfunction.

Authors:  André Luis Bombeiro; Lígia Antunes Gonçalves; Carlos Penha-Gonçalves; Claudio Romero Farias Marinho; Maria Regina D'Império Lima; Gerson Chadi; José Maria Álvarez
Journal:  PLoS One       Date:  2012-11-12       Impact factor: 3.240

  4 in total

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