| Literature DB >> 7966224 |
S V Joag1, R J Adams, L Foresman, D Galbreath, M C Zink, D M Pinson, H McClure, O Narayan.
Abstract
We studied 15 macaques inoculated with SIV and identified three phases of infection. Phase 1 was characterized by activated lymphocytes in blood and infected cells in the CSF. In phase 2, activated cells were not detected but virus was recovered from mitogen-stimulated PBMC, while in phase 3, virus was recovered from mitogen-stimulated PBMC only after depletion of CD8+ lymphocytes, indicating effective control of the virus in peripheral blood. Early development of phase 3 status correlated with a longer period of clinical normalcy.Entities:
Mesh：
Year: 1994 PMID： 7966224 DOI： 10.1111/j.1600-0684.1994.tb00110.x
Source DB: PubMed Journal: J Med Primatol ISSN： 0047-2565 Impact factor: 0.667