Literature DB >> 7965453

Ratios of linoleic acid to alpha-linolenic acid in formulas for term infants.

R A Gibson1, M Makrides, M A Neumann, K Simmer, E Mantzioris, M J James.   

Abstract

Commercial infant formulas with a ratio of linoleic acid (LA) to alpha-linolenic acid (ALA) of 10:1 or higher are nutritionally inadequate; the tissue levels of docosahexaenoic acid (DHA) are lower and the visual function indices are reduced in infants who are fed these formulas. All the evidence points to using LA:ALA ratios of less than 8:1, but there has been only one study in infants that used formulas with reduced LA:ALA ratios, and only biochemical indices were monitored. There is a need for both short-term studies to establish the ratios of LA to ALA that will make possible the accumulation of DHA to levels close to those in breast-fed infants and long-term trials to determine the effects of such fat blends on growth and development.

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Year:  1994        PMID: 7965453     DOI: 10.1016/s0022-3476(06)80736-5

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  3 in total

Review 1.  Effect of dietary docosahexaenoic acid on brain composition and neural function in term infants.

Authors:  R A Gibson; M A Neumann; M Makrides
Journal:  Lipids       Date:  1996-03       Impact factor: 1.880

2.  Erythrocyte fatty acids of term infants fed either breast milk, standard formula, or formula supplemented with long-chain polyunsaturates.

Authors:  M Makrides; M A Neumann; K Simmer; R A Gibson
Journal:  Lipids       Date:  1995-10       Impact factor: 1.880

3.  Quantification of Nervonic Acid in Human Milk in the First 30 Days of Lactation: Influence of Lactation Stages and Comparison with Infant Formulae.

Authors:  Jiahui Yu; Tinglan Yuan; Xinghe Zhang; Qingzhe Jin; Wei Wei; Xingguo Wang
Journal:  Nutrients       Date:  2019-08-14       Impact factor: 5.717

  3 in total

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