| Literature DB >> 7965453 |
R A Gibson1, M Makrides, M A Neumann, K Simmer, E Mantzioris, M J James.
Abstract
Commercial infant formulas with a ratio of linoleic acid (LA) to alpha-linolenic acid (ALA) of 10:1 or higher are nutritionally inadequate; the tissue levels of docosahexaenoic acid (DHA) are lower and the visual function indices are reduced in infants who are fed these formulas. All the evidence points to using LA:ALA ratios of less than 8:1, but there has been only one study in infants that used formulas with reduced LA:ALA ratios, and only biochemical indices were monitored. There is a need for both short-term studies to establish the ratios of LA to ALA that will make possible the accumulation of DHA to levels close to those in breast-fed infants and long-term trials to determine the effects of such fat blends on growth and development.Entities:
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Year: 1994 PMID: 7965453 DOI: 10.1016/s0022-3476(06)80736-5
Source DB: PubMed Journal: J Pediatr ISSN: 0022-3476 Impact factor: 4.406