Literature DB >> 7964923

Design of potential angiogenin inhibitors.

B J Howlin1, N P Tomkinson, J Chen, G A Webb.   

Abstract

A model of angiogenin has been prepared by homology modelling, based upon the structure of ribonuclease A. This model has been used to postulate an inhibitor based upon the angiostatic agent TAN1120. The complex of ribonuclease A with a dinucleotide has been modelled and used as a guide to the binding orientation of daunomycin--the closest TAN1120 analogue for which the crystal structure and stereochemistry are available.

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Year:  1994        PMID： 7964923     DOI： 10.1007/BF00126741

Source DB:  PubMed          Journal:  J Comput Aided Mol Des        ISSN： 0920-654X            Impact factor:   3.686


  10 in total

1.  Crystallization and preliminary X-ray analysis of human angiogenin.

Authors:  K R Acharya; V Subramanian; R Shapiro; J F Riordan; B L Vallee
Journal:  J Mol Biol       Date:  1992-12-20       Impact factor: 5.469

Review 2.  Regulators of angiogenesis.

Authors:  M Klagsbrun; P A D'Amore
Journal:  Annu Rev Physiol       Date:  1991       Impact factor: 19.318

3.  The Protein Data Bank: a computer-based archival file for macromolecular structures.

Authors:  F C Bernstein; T F Koetzle; G J Williams; E F Meyer; M D Brice; J R Rodgers; O Kennard; T Shimanouchi; M Tasumi
Journal:  J Mol Biol       Date:  1977-05-25       Impact factor: 5.469

4.  Characteristic ribonucleolytic activity of human angiogenin.

Authors:  R Shapiro; J F Riordan; B L Vallee
Journal:  Biochemistry       Date:  1986-06-17       Impact factor: 3.162

5.  A preliminary three-dimensional structure of angiogenin.

Authors:  K A Palmer; H A Scheraga; J F Riordan; B L Vallee
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

Review 6.  Prediction of the secondary structure of proteins from their amino acid sequence.

Authors:  P Y Chou; G D Fasman
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1978

7.  Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells.

Authors:  J W Fett; D J Strydom; R R Lobb; E M Alderman; J L Bethune; J F Riordan; B L Vallee
Journal:  Biochemistry       Date:  1985-09-24       Impact factor: 3.162

8.  Site-directed mutagenesis of histidine-13 and histidine-114 of human angiogenin. Alanine derivatives inhibit angiogenin-induced angiogenesis.

Authors:  R Shapiro; B L Vallee
Journal:  Biochemistry       Date:  1989-09-05       Impact factor: 3.162

9.  Nuclear magnetic resonance and neutron diffraction studies of the complex of ribonuclease A with uridine vanadate, a transition-state analogue.

Authors:  B Borah; C W Chen; W Egan; M Miller; A Wlodawer; J S Cohen
Journal:  Biochemistry       Date:  1985-04-09       Impact factor: 3.162

Review 10.  Structure and function of ribonuclease A binding subsites.

Authors:  X Parés; M V Nogués; R de Llorens; C M Cuchillo
Journal:  Essays Biochem       Date:  1991       Impact factor: 8.000
  10 in total

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