Literature DB >> 7964568

A fatal ketamine poisoning.

M Licata1, G Pierini, G Popoli.   

Abstract

An unusual case of death by ketamine overdose is reported. The drug's administration was a homicide for homosexual ends. Authors discuss a rapid and effective solid-phase extraction procedure using Bond-Elute* C18 for Ketamine and Nor-Ketamine detection in biological fluids and tissues with a 75% recovery. The drug analysis was carried out by the means of gas-chromatography (GLC) and gas-chromatography/mass spectrometry (GC-MS). The yield of the procedure for Ketamine was: blood 27.4 micrograms/mL; urine 8.51 micrograms/mL; bile 15.2 micrograms/mL; brain 3.24 micrograms/mL; liver 6.6 micrograms/mL; kidney 3.38 micrograms/mL. Nor-Ketamine was detected in all samples, but not quantified.

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Year:  1994        PMID： 7964568

Source DB:  PubMed          Journal:  J Forensic Sci        ISSN： 0022-1198            Impact factor:   1.832


  5 in total

1.  Ketamine-induced ventricular structural, sympathetic and electrophysiological remodelling: pathological consequences and protective effects of metoprolol.

Authors:  Y Li; J Shi; B F Yang; L Liu; C L Han; W M Li; D L Dong; Z W Pan; G Z Liu; J Q Geng; L Sheng; X Y Tan; D H Sun; Z H Gong; Y T Gong
Journal:  Br J Pharmacol       Date:  2012-03       Impact factor: 8.739

2.  Dual regulation by ethanol of the inhibitory effects of ketamine on spinal NMDA-induced pressor responses in rats.

Authors:  Nien-Tzu Keng; Hsun-Hsun Lin; Huei-Ru Lin; Wei-Kung Hsieh; Chih-Chia Lai
Journal:  J Biomed Sci       Date:  2012-02-02       Impact factor: 8.410

3.  Toxicokinetic/Toxicodynamic Interaction Studies in Rats between the Drugs of Abuse γ-Hydroxybutyric Acid and Ketamine and Treatment Strategies for Overdose.

Authors:  Nisha V Kwatra; Marilyn E Morris
Journal:  Pharmaceutics       Date:  2021-05-18       Impact factor: 6.321

4.  Ketamine-mediated afferent-specific presynaptic transmission blocks in low-threshold and sex-specific subpopulation of myelinated Ah-type baroreceptor neurons of rats.

Authors:  Lu-Qi Wang; Sheng-Zhi Liu; Xin Wen; Di Wu; Lei Yin; Yao Fan; Ye Wang; Wei-Ran Chen; Pei Chen; Yang Liu; Xiao-Long Lu; Hong-Li Sun; Weinian Shou; Guo-Fen Qiao; Bai-Yan Li
Journal:  Oncotarget       Date:  2015-12-29

5.  Recreational ketamine-related deaths notified to the National Programme on Substance Abuse Deaths, England, 1997-2019.

Authors:  John Martin Corkery; Wan-Chu Hung; Hugh Claridge; Christine Goodair; Caroline S Copeland; Fabrizio Schifano
Journal:  J Psychopharmacol       Date:  2021-06-05       Impact factor: 4.153
  5 in total

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