Literature DB >> 7963117

Lessons learned from data logging in a multicenter clinical trial using a late-generation implantable cardioverter-defibrillator. The Guardian ATP 4210 Multicenter Investigators Group.

M A Wood1, B S Stambler, R J Damiano, P Greenway, K A Ellenbogen.   

Abstract

OBJECTIVES: This study examined patterns of implantable cardioverter-defibrillator use as documented by data logging.
BACKGROUND: Implantable cardioverter-defibrillators are accepted therapy for malignant ventricular tachyarrhythmias; however, relatively little is known about their patterns of use. Incorporation of data-storage capacities into these devices provides insight into long-term defibrillator function.
METHODS: Stored data-logging information was retrieved from 401 implanted cardioverter-defibrillators in 393 patients over an average of 303 days of follow-up.
RESULTS: A total of 91,443 detections were recorded in 299 patients. One hundred-six patients (26%) had detections due to supraventricular tachycardias, electrical noise or other causes, resulting in inappropriate therapy delivery to 92 patients (23%). Two hundred eighty-one patients recorded 66,276 episodes of ventricular tachycardia or ventricular fibrillation. Of these, 74.4% episodes terminated spontaneously without any delivered therapy, 22.1% terminated after antitachycardia pacing, and 1.7% terminated after shock therapy. Antitachycardia pacing was activated without formal testing in 47% of all patients receiving this therapy and was successful in 96% of all episodes receiving this therapy. Acceleration of tachycardia to shock therapy occurred in 1.3% of all episodes and in 30.5% of patients receiving antitachycardia pacing. Thirty-four patients (8.7%) died during follow-up. Mortality was associated with patient age, heart failure functional class at implantation and frequency of shocks received during follow-up (all p < or = 0.05).
CONCLUSIONS: Most ventricular tachyarrhythmia detections by this noncommitted implantable cardioverter-defibrillator resolve spontaneously, whereas the majority receiving therapy can be treated with antitachycardia pacing. Mortality after implantable cardioverter-defibrillator implantation is associated with age, heart failure class and frequency of shocks received during follow-up. Data-logging capabilities provide valuable insights into the patterns of defibrillator use.

Entities:  

Mesh:

Year:  1994        PMID: 7963117     DOI: 10.1016/0735-1097(94)90176-7

Source DB:  PubMed          Journal:  J Am Coll Cardiol        ISSN: 0735-1097            Impact factor:   24.094


  10 in total

Review 1.  Implantable dual-chamber cardioverter-defibrillator-pacemaker.

Authors:  D Pfeiffer; M Mende; A Hagendorff
Journal:  Curr Cardiol Rep       Date:  2000-07       Impact factor: 2.931

2.  Predictors of ventricular tachycardia recurrence in 100 patients receiving tiered therapy defibrillators.

Authors:  X F Costeas; M S Link; C B Foote; M K Homoud; P J Wang; N A Estes
Journal:  Clin Cardiol       Date:  2000-11       Impact factor: 2.882

Review 3.  Mechanisms of sudden cardiac death: oxidants and metabolism.

Authors:  Kai-Chien Yang; John W Kyle; Jonathan C Makielski; Samuel C Dudley
Journal:  Circ Res       Date:  2015-06-05       Impact factor: 17.367

4.  Phantom shocks unmasked: clinical data and proposed mechanism of memory reactivation of past traumatic shocks in patients with implantable cardioverter defibrillators.

Authors:  Sony Jacob; Sidakpal S Panaich; Sandip K Zalawadiya; George McKelvey; George Abraham; Rajeev Aravindhakshan; Samuel F Sears; Jamie B Conti; H Michael Marsh
Journal:  J Interv Card Electrophysiol       Date:  2011-12-21       Impact factor: 1.900

Review 5.  The post-cardiac arrest syndrome: A case for lung-brain coupling and opportunities for neuroprotection.

Authors:  Nguyen Mai; Kathleen Miller-Rhodes; Sara Knowlden; Marc W Halterman
Journal:  J Cereb Blood Flow Metab       Date:  2019-03-13       Impact factor: 6.200

6.  [New algorithms for discrimination between supraventricular and ventricular tachyarrhythmias in patients with implantable cardioverter/defibrillator].

Authors:  J Neuzner; M Schlepper
Journal:  Herzschrittmacherther Elektrophysiol       Date:  1997-03

Review 7.  Prevalence and incidence of arrhythmias and sudden death in heart failure.

Authors:  John G F Cleland; Sudipta Chattopadhyay; Aleem Khand; Timothy Houghton; Gerald C Kaye
Journal:  Heart Fail Rev       Date:  2002-07       Impact factor: 4.214

8.  Endovascular renal denervation: a novel sympatholytic with relevance to chronic kidney disease.

Authors:  Neil A Hoye; James C Baldi; Tracey L Putt; John B Schollum; Gerard T Wilkins; Robert J Walker
Journal:  Clin Kidney J       Date:  2013-11-08

9.  Prevention of ventricular fibrillation through de-networking of the Purkinje system: Proof-of-Concept Paper on the Substrate Modification of the Purkinje Network.

Authors:  Guram Imnadze; Thomas Zerm
Journal:  Pacing Clin Electrophysiol       Date:  2019-09-03       Impact factor: 1.976

10.  Elimination of Purkinje Fibers by Electroporation Reduces Ventricular Fibrillation Vulnerability.

Authors:  Christopher Livia; Alan Sugrue; Tyra Witt; Murray D Polkinghorne; Elad Maor; Suraj Kapa; Helge I Lehmann; Christopher V DeSimone; Atta Behfar; Samuel J Asirvatham; Christopher J McLeod
Journal:  J Am Heart Assoc       Date:  2018-08-07       Impact factor: 5.501

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.