OBJECTIVE: Percutaneous injection of ethanol was evaluated in terminally ill cancer patients with painful osteolytic bone metastases treated previously without success by radiation or chemotherapy and conventional pain therapy. METHODS AND MATERIALS: Twenty-five patients with 27 bone metastases in various locations underwent one to three instillations of 3-25 ml ethanol (95%) under CT guidance, which allowed precise needle positioning and control of the diffusion of alcohol thus minimizing the complications. RESULTS: Within 24 to 48 h 74% of the cases experienced a reduction of analgesic needs. CONCLUSION: Percutaneous ethanol injection under CT guidance is useful in reducing pain and in improving the quality of life of patients with advanced stages of cancer and painful bone metastases.
OBJECTIVE: Percutaneous injection of ethanol was evaluated in terminally ill cancerpatients with painful osteolytic bone metastases treated previously without success by radiation or chemotherapy and conventional pain therapy. METHODS AND MATERIALS: Twenty-five patients with 27 bone metastases in various locations underwent one to three instillations of 3-25 ml ethanol (95%) under CT guidance, which allowed precise needle positioning and control of the diffusion of alcohol thus minimizing the complications. RESULTS: Within 24 to 48 h 74% of the cases experienced a reduction of analgesic needs. CONCLUSION: Percutaneous ethanol injection under CT guidance is useful in reducing pain and in improving the quality of life of patients with advanced stages of cancer and painful bone metastases.
Authors: Matthew R Callstrom; J William Charboneau; Matthew P Goetz; Joseph Rubin; Thomas D Atwell; Michael A Farrell; Timothy J Welch; Timothy P Maus Journal: Skeletal Radiol Date: 2005-10-05 Impact factor: 2.199
Authors: Michael David Lane; Huy B Q Le; Steven Lee; Casey Young; Manraj K S Heran; Maziar Badii; Paul William Clarkson; Peter L Munk Journal: Skeletal Radiol Date: 2010-08-05 Impact factor: 2.199
Authors: G Carrafiello; D Laganà; C Pellegrino; F Fontana; M Mangini; P Nicotera; M Petullà; E Bracchi; E Genovese; S Cuffari; C Fugazzola Journal: Radiol Med Date: 2009-05-14 Impact factor: 3.469
Authors: Matthew R Callstrom; Damian E Dupuy; Stephen B Solomon; Robert A Beres; Peter J Littrup; Kirkland W Davis; Ricardo Paz-Fumagalli; Cheryl Hoffman; Thomas D Atwell; J William Charboneau; Grant D Schmit; Matthew P Goetz; Joseph Rubin; Kathy J Brown; Paul J Novotny; Jeff A Sloan Journal: Cancer Date: 2012-10-12 Impact factor: 6.860