Literature DB >> 7960676

Antiphospholipid antibodies and cerebral artery dissection: two frequent causes of brain ischemia in young adults.

F Girmenia1, C Argentino, E Di Scipio, F Orzi, C Pozzilli, M Rasura, J Faroni, G Valesini, C Fieschi.   

Abstract

As part of a multicenter study on ischemic stroke in the young, we report the occurrence of high antiphospholipid antibody (aPLs) levels and cerebral dissection in 75 patients. These represent the two most frequent non-thromboembolic causes of cerebral ischemia in our population. Increased aPL titres were found in nine cases (12%); cerebral artery dissection in eleven (14%). Our data stress the need to modify the classical diagnostic approach to cerebral ischemia by including hematological assessments and new neuroimaging techniques as screening tests.

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Year:  1994        PMID: 7960676     DOI: 10.1007/BF02342452

Source DB:  PubMed          Journal:  Ital J Neurol Sci        ISSN: 0392-0461


  23 in total

1.  Non-invasive diagnosis of internal carotid artery dissections.

Authors:  W Müllges; E B Ringelstein; M Leibold
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-02       Impact factor: 10.154

2.  Special report. The Second International Anti-cardiolipin Standardization Workshop/the Kingston Anti-Phospholipid Antibody Study (KAPS) group.

Authors:  E N Harris
Journal:  Am J Clin Pathol       Date:  1990-10       Impact factor: 2.493

Review 3.  The role of antiphospholipid antibodies in stroke.

Authors:  B M Coull; S R Levine; R L Brey
Journal:  Neurol Clin       Date:  1992-02       Impact factor: 3.806

Review 4.  Antiphospholipid antibodies and ischemic cerebrovascular disease.

Authors:  S R Levine; R L Brey
Journal:  Semin Neurol       Date:  1991-12       Impact factor: 3.420

5.  Thrombosis in systemic lupus erythematosus: striking association with the presence of circulating lupus anticoagulant.

Authors:  M L Boey; C B Colaco; A E Gharavi; K B Elkon; S Loizou; G R Hughes
Journal:  Br Med J (Clin Res Ed)       Date:  1983-10-08

6.  Neurological disease associated with antiphospholipid antibodies.

Authors:  D P Briley; B M Coull; S H Goodnight
Journal:  Ann Neurol       Date:  1989-03       Impact factor: 10.422

7.  Migraine and anti-phospholipid antibodies.

Authors:  A Shuaib; L Barklay; M A Lee; O Suchowersky
Journal:  Headache       Date:  1989-01       Impact factor: 5.887

8.  High prevalence of anti-cardiolipin and other autoantibodies in a healthy elderly population.

Authors:  M N Manoussakis; A G Tzioufas; M P Silis; P J Pange; J Goudevenos; H M Moutsopoulos
Journal:  Clin Exp Immunol       Date:  1987-09       Impact factor: 4.330

9.  Diagnosis and treatment of vertebral aneurysms.

Authors:  A Yamaura
Journal:  J Neurosurg       Date:  1988-09       Impact factor: 5.115

10.  Ischemic stroke in adults younger than 30 years of age. Cause and prognosis.

Authors:  J Bogousslavsky; F Regli
Journal:  Arch Neurol       Date:  1987-05
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