| Literature DB >> 7959935 |
R Anand1, G K Patnaik, D K Kulshreshtha, B N Dhawan.
Abstract
An ethanolic extract of the fruits of T. terrestris showed significant dose dependent protection against uroliths induced by glass bead implantation in albino rats. On subsequent fractionation of the ethanol extract, maximum activity was localised in the 10% aqueous methanol fraction. It provided significant protection against deposition of calculogenic material around the glass bead. It also protected leucocytosis and elevation in serum urea levels. Further, fractionation lead to decreased activity. This could be either due to loss of active compounds during fractionation, or the antiurolithiatic activity of T. terrestris being a combined effect of several constituents present in the methanolic fraction.Entities:
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Year: 1994 PMID: 7959935
Source DB: PubMed Journal: Indian J Exp Biol ISSN: 0019-5189 Impact factor: 0.818