Literature DB >> 7959935

Activity of certain fractions of Tribulus terrestris fruits against experimentally induced urolithiasis in rats.

R Anand1, G K Patnaik, D K Kulshreshtha, B N Dhawan.   

Abstract

An ethanolic extract of the fruits of T. terrestris showed significant dose dependent protection against uroliths induced by glass bead implantation in albino rats. On subsequent fractionation of the ethanol extract, maximum activity was localised in the 10% aqueous methanol fraction. It provided significant protection against deposition of calculogenic material around the glass bead. It also protected leucocytosis and elevation in serum urea levels. Further, fractionation lead to decreased activity. This could be either due to loss of active compounds during fractionation, or the antiurolithiatic activity of T. terrestris being a combined effect of several constituents present in the methanolic fraction.

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Year:  1994        PMID: 7959935

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN: 0019-5189            Impact factor:   0.818


  8 in total

1.  Inhibition of the growth of urinary calcium hydrogen phosphate dihydrate crystals with aqueous extracts of Tribulus terrestris and Bergenia ligulata.

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Journal:  Urol Res       Date:  2005-03-25

2.  Effect of Costus igneus stem extract on calcium oxalate urolithiasis in albino rats.

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Journal:  Urol Res       Date:  2012-10

Review 3.  Herbal medicines in the management of urolithiasis: alternative or complementary?

Authors:  Veronika Butterweck; Saeed R Khan
Journal:  Planta Med       Date:  2009-05-14       Impact factor: 3.352

4.  Prospective randomized clinical trial comparing phytotherapy with potassium citrate in management of minimal burden (≤8 mm) nephrolithiasis.

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Journal:  Urol Ann       Date:  2011-05

Review 5.  Phytopharmacological overview of Tribulus terrestris.

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Journal:  Pharmacogn Rev       Date:  2014-01

Review 6.  Effects of Tribulus terrestris L. on Sport and Health Biomarkers in Physically Active Adult Males: A Systematic Review.

Authors:  Diego Fernández-Lázaro; Cesar I Fernandez-Lazaro; Jesús Seco-Calvo; Evelina Garrosa; David P Adams; Juan Mielgo-Ayuso
Journal:  Int J Environ Res Public Health       Date:  2022-08-03       Impact factor: 4.614

7.  Current status of herbal drugs in India: an overview.

Authors:  Ashok D B Vaidya; Thomas P A Devasagayam
Journal:  J Clin Biochem Nutr       Date:  2007-07       Impact factor: 3.114

8.  Antiurolithiatic effect of lithocare against ethylene glycol-induced urolithiasis in Wistar rats.

Authors:  Sumaiya I Lulat; Yogesh Chand Yadav; R Balaraman; Rajesh Maheshwari
Journal:  Indian J Pharmacol       Date:  2016 Jan-Feb       Impact factor: 1.200

  8 in total

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